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Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis.
Lopez T, Hanahan D. Lopez T, et al. Among authors: hanahan d. Cancer Cell. 2002 May;1(4):339-53. doi: 10.1016/s1535-6108(02)00055-7. Cancer Cell. 2002. PMID: 12086849
The hallmarks of cancer.
Hanahan D, Weinberg RA. Hanahan D, et al. Cell. 2000 Jan 7;100(1):57-70. doi: 10.1016/s0092-8674(00)81683-9. Cell. 2000. PMID: 10647931 Review. No abstract available.
Fibroblast growth factor receptor 4, implicated in progression of islet cell carcinogenesis by its expression profile, does not contribute functionally.
Olson DC, Deng C, Hanahan D. Olson DC, et al. Among authors: hanahan d. Cell Growth Differ. 1998 Jul;9(7):557-64. Cell Growth Differ. 1998. PMID: 9690623
Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas.
Hodgson G, Hager JH, Volik S, Hariono S, Wernick M, Moore D, Nowak N, Albertson DG, Pinkel D, Collins C, Hanahan D, Gray JW. Hodgson G, et al. Among authors: hanahan d. Nat Genet. 2001 Dec;29(4):459-64. doi: 10.1038/ng771. Nat Genet. 2001. PMID: 11694878
Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance.
Smith KM, Olson DC, Hirose R, Hanahan D. Smith KM, et al. Among authors: hanahan d. Int Immunol. 1997 Sep;9(9):1355-65. doi: 10.1093/intimm/9.9.1355. Int Immunol. 1997. PMID: 9310839
T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus.
Jolicoeur C, Hanahan D, Smith KM. Jolicoeur C, et al. Among authors: hanahan d. Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6707-11. doi: 10.1073/pnas.91.14.6707. Proc Natl Acad Sci U S A. 1994. PMID: 8022837 Free PMC article.
Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorigenesis.
Bergers G, Hanahan D, Coussens LM. Bergers G, et al. Among authors: hanahan d. Int J Dev Biol. 1998;42(7):995-1002. Int J Dev Biol. 1998. PMID: 9853830 Review.
Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice.
Onrust SV, Hartl PM, Rosen SD, Hanahan D. Onrust SV, et al. Among authors: hanahan d. J Clin Invest. 1996 Jan 1;97(1):54-64. doi: 10.1172/JCI118406. J Clin Invest. 1996. PMID: 8550850 Free PMC article.
Proliferation, senescence, and neoplastic progression of beta cells in hyperplasic pancreatic islets.
Teitelman G, Alpert S, Hanahan D. Teitelman G, et al. Among authors: hanahan d. Cell. 1988 Jan 15;52(1):97-105. doi: 10.1016/0092-8674(88)90534-x. Cell. 1988. PMID: 2894250
Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion.
Shi Y, Kanaani J, Menard-Rose V, Ma YH, Chang PY, Hanahan D, Tobin A, Grodsky G, Baekkeskov S. Shi Y, et al. Among authors: hanahan d. Am J Physiol Endocrinol Metab. 2000 Sep;279(3):E684-94. doi: 10.1152/ajpendo.2000.279.3.E684. Am J Physiol Endocrinol Metab. 2000. PMID: 10950838
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