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81 results
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Metal ion dependency of microfibrils supports a rod-like conformation for fibrillin-1 calcium-binding epidermal growth factor-like domains.
Cardy CM, Handford PA. Cardy CM, et al. Among authors: handford pa. J Mol Biol. 1998 Mar 13;276(5):855-60. doi: 10.1006/jmbi.1997.1593. J Mol Biol. 1998. PMID: 9566191
The three-dimensional structure of the first EGF-like module of human factor IX: comparison with EGF and TGF-alpha.
Baron M, Norman DG, Harvey TS, Handford PA, Mayhew M, Tse AG, Brownlee GG, Campbell ID. Baron M, et al. Among authors: handford pa. Protein Sci. 1992 Jan;1(1):81-90. doi: 10.1002/pro.5560010109. Protein Sci. 1992. PMID: 1304885 Free PMC article.
Ligand requirements for Ca2+ binding to EGF-like domains.
Mayhew M, Handford P, Baron M, Tse AG, Campbell ID, Brownlee GG. Mayhew M, et al. Protein Eng. 1992 Sep;5(6):489-94. doi: 10.1093/protein/5.6.489. Protein Eng. 1992. PMID: 1438159
Protein engineering of the propeptide of human factor IX.
Handford PA, Winship PR, Brownlee GG. Handford PA, et al. Protein Eng. 1991 Feb;4(3):319-23. doi: 10.1093/protein/4.3.319. Protein Eng. 1991. PMID: 1857716
Calcium binding to fibrillin?
Handford PA, Mayhew M, Brownlee GG. Handford PA, et al. Nature. 1991 Oct 3;353(6343):395. doi: 10.1038/353395a0. Nature. 1991. PMID: 1896084 No abstract available.
Key residues involved in calcium-binding motifs in EGF-like domains.
Handford PA, Mayhew M, Baron M, Winship PR, Campbell ID, Brownlee GG. Handford PA, et al. Nature. 1991 May 9;351(6322):164-7. doi: 10.1038/351164a0. Nature. 1991. PMID: 2030732
The first EGF-like domain from human factor IX contains a high-affinity calcium binding site.
Handford PA, Baron M, Mayhew M, Willis A, Beesley T, Brownlee GG, Campbell ID. Handford PA, et al. EMBO J. 1990 Feb;9(2):475-80. EMBO J. 1990. PMID: 2406129 Free PMC article.
The role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX.
Rees DJ, Jones IM, Handford PA, Walter SJ, Esnouf MP, Smith KJ, Brownlee GG. Rees DJ, et al. Among authors: handford pa. EMBO J. 1988 Jul;7(7):2053-61. EMBO J. 1988. PMID: 3262057 Free PMC article.
The structure of a Ca(2+)-binding epidermal growth factor-like domain: its role in protein-protein interactions.
Rao Z, Handford P, Mayhew M, Knott V, Brownlee GG, Stuart D. Rao Z, et al. Cell. 1995 Jul 14;82(1):131-41. doi: 10.1016/0092-8674(95)90059-4. Cell. 1995. PMID: 7606779
Protein engineering of the hydrophobic domain of human factor IX.
Hughes PE, Handford PA, Austen DE, Brownlee GG. Hughes PE, et al. Among authors: handford pa. Protein Eng. 1994 Sep;7(9):1121-7. doi: 10.1093/protein/7.9.1121. Protein Eng. 1994. PMID: 7831283
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