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The role of host genetics in leishmaniasis.
Sakthianandeswaren A, Foote SJ, Handman E. Sakthianandeswaren A, et al. Among authors: handman e. Trends Parasitol. 2009 Aug;25(8):383-91. doi: 10.1016/ Epub 2009 Jul 18. Trends Parasitol. 2009. PMID: 19617002 Review.
Crystal structure of the Leishmania major MIX protein: a scaffold protein that mediates protein-protein interactions.
Gorman MA, Uboldi AD, Walsh PJ, Tan KS, Hansen G, Huyton T, Ji H, Curtis J, Kedzierski L, Papenfuss AT, Dogovski C, Perugini MA, Simpson RJ, Handman E, Parker MW. Gorman MA, et al. Among authors: handman e. Protein Sci. 2011 Jun;20(6):1060-8. doi: 10.1002/pro.631. Epub 2011 Apr 27. Protein Sci. 2011. PMID: 21465610 Free PMC article.
The molecular basis of Leishmania pathogenesis.
McConville MJ, Handman E. McConville MJ, et al. Among authors: handman e. Int J Parasitol. 2007 Aug;37(10):1047-51. doi: 10.1016/S0020-7519(07)00216-0. Int J Parasitol. 2007. PMID: 17629957 No abstract available.
A mitochondrial protein affects cell morphology, mitochondrial segregation and virulence in Leishmania.
Uboldi AD, Lueder FB, Walsh P, Spurck T, McFadden GI, Curtis J, Likic VA, Perugini MA, Barson M, Lithgow T, Handman E. Uboldi AD, et al. Among authors: handman e. Int J Parasitol. 2006 Dec;36(14):1499-514. doi: 10.1016/j.ijpara.2006.08.006. Epub 2006 Sep 15. Int J Parasitol. 2006. PMID: 17011565
Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms.
Kedzierski L, Malby RL, Smith BJ, Perugini MA, Hodder AN, Ilg T, Colman PM, Handman E. Kedzierski L, et al. Among authors: handman e. J Mol Biol. 2006 Oct 13;363(1):215-27. doi: 10.1016/j.jmb.2006.08.023. Epub 2006 Aug 12. J Mol Biol. 2006. PMID: 16963079
Genes and susceptibility to leishmaniasis.
Handman E, Elso C, Foote S. Handman E, et al. Adv Parasitol. 2005;59:1-75. doi: 10.1016/S0065-308X(05)59001-8. Adv Parasitol. 2005. PMID: 16182864 Review.
Characterisation of a Leishmania mexicana knockout lacking guanosine diphosphate-mannose pyrophosphorylase.
Stewart J, Curtis J, Spurck TP, Ilg T, Garami A, Baldwin T, Courret N, McFadden GI, Davis A, Handman E. Stewart J, et al. Among authors: handman e. Int J Parasitol. 2005 Jul;35(8):861-73. doi: 10.1016/j.ijpara.2005.03.008. Int J Parasitol. 2005. PMID: 15936761
SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function.
Brender C, Columbus R, Metcalf D, Handman E, Starr R, Huntington N, Tarlinton D, Ødum N, Nicholson SE, Nicola NA, Hilton DJ, Alexander WS. Brender C, et al. Among authors: handman e. Mol Cell Biol. 2004 Jul;24(13):6094-103. doi: 10.1128/MCB.24.13.6094-6103.2004. Mol Cell Biol. 2004. PMID: 15199163 Free PMC article.
Leucine-rich repeats in host-pathogen interactions.
Kedzierski Ł, Montgomery J, Curtis J, Handman E. Kedzierski Ł, et al. Among authors: handman e. Arch Immunol Ther Exp (Warsz). 2004 Mar-Apr;52(2):104-12. Arch Immunol Ther Exp (Warsz). 2004. PMID: 15179324 Review.
A leucine-rich repeat motif of Leishmania parasite surface antigen 2 binds to macrophages through the complement receptor 3.
Kedzierski L, Montgomery J, Bullen D, Curtis J, Gardiner E, Jimenez-Ruiz A, Handman E. Kedzierski L, et al. Among authors: handman e. J Immunol. 2004 Apr 15;172(8):4902-6. doi: 10.4049/jimmunol.172.8.4902. J Immunol. 2004. PMID: 15067069
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