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Peroxisome proliferator-activated-γ coactivator-1α-mediated mitochondrial biogenesis is important for hematopoietic recovery in response to stress.
Basu S, Broxmeyer HE, Hangoc G. Basu S, et al. Among authors: hangoc g. Stem Cells Dev. 2013 Jun 1;22(11):1678-92. doi: 10.1089/scd.2012.0466. Epub 2013 Feb 13. Stem Cells Dev. 2013. PMID: 23311338 Free PMC article.
Nonmarrow hematopoiesis occurs in a hyaluronic-acid-rich node and duct system in mice.
Hwang S, Lee SJ, Park SH, Chitteti BR, Srour EF, Cooper S, Hangoc G, Broxmeyer HE, Kwon BS. Hwang S, et al. Among authors: hangoc g. Stem Cells Dev. 2014 Nov 1;23(21):2661-71. doi: 10.1089/scd.2014.0075. Epub 2014 Jul 14. Stem Cells Dev. 2014. PMID: 24914588 Free PMC article.
Mild Heat Treatment Primes Human CD34(+) Cord Blood Cells for Migration Toward SDF-1α and Enhances Engraftment in an NSG Mouse Model.
Capitano ML, Hangoc G, Cooper S, Broxmeyer HE. Capitano ML, et al. Among authors: hangoc g. Stem Cells. 2015 Jun;33(6):1975-84. doi: 10.1002/stem.1988. Stem Cells. 2015. PMID: 25753525 Free PMC article.
Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis.
Broxmeyer HE, Hoggatt J, O'Leary HA, Mantel C, Chitteti BR, Cooper S, Messina-Graham S, Hangoc G, Farag S, Rohrabaugh SL, Ou X, Speth J, Pelus LM, Srour EF, Campbell TB. Broxmeyer HE, et al. Among authors: hangoc g. Nat Med. 2012 Dec;18(12):1786-96. doi: 10.1038/nm.2991. Epub 2012 Nov 18. Nat Med. 2012. PMID: 23160239 Free PMC article.
Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation.
Campbell TB, Basu S, Hangoc G, Tao W, Broxmeyer HE. Campbell TB, et al. Among authors: hangoc g. Blood. 2009 Oct 15;114(16):3392-401. doi: 10.1182/blood-2008-12-195214. Epub 2009 Aug 18. Blood. 2009. PMID: 19690340 Free PMC article.
Enhanced functional response to CXCL12/SDF-1 through retroviral overexpression of CXCR4 on M07e cells: implications for hematopoietic stem cell transplantation.
Porecha NK, English K, Hangoc G, Broxmeyer HE, Christopherson KW 2nd. Porecha NK, et al. Among authors: hangoc g. Stem Cells Dev. 2006 Jun;15(3):325-33. doi: 10.1089/scd.2006.15.325. Stem Cells Dev. 2006. PMID: 16846371
CD26 is essential for normal G-CSF-induced progenitor cell mobilization as determined by CD26-/- mice.
Christopherson KW, Cooper S, Hangoc G, Broxmeyer HE. Christopherson KW, et al. Among authors: hangoc g. Exp Hematol. 2003 Nov;31(11):1126-34. doi: 10.1016/j.exphem.2003.07.002. Exp Hematol. 2003. PMID: 14585379
G-CSF treatment of WT mice resulted in the mobilization of HPC into the peripheral blood. The number of HPC detected in G-CSF-treated CD26(-/-) mouse peripheral blood was significantly less than the corresponding number of HPC detected in G-CSF-treated WT mou
G-CSF treatment of WT mice resulted in the mobilization of HPC into the peripheral blood. The number of HPC detected in G-CSF-
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.
Broxmeyer HE, Orschell CM, Clapp DW, Hangoc G, Cooper S, Plett PA, Liles WC, Li X, Graham-Evans B, Campbell TB, Calandra G, Bridger G, Dale DC, Srour EF. Broxmeyer HE, et al. Among authors: hangoc g. J Exp Med. 2005 Apr 18;201(8):1307-18. doi: 10.1084/jem.20041385. J Exp Med. 2005. PMID: 15837815 Free PMC article.
AMD3100 induced rapid mobilization of mouse and human HPCs and synergistically augmented G-CSF-induced mobilization of HPCs. ...AMD3100 synergized with G-CSF to mobilize murine LTR cells and human SCID repopulating cells (SRCs). Human CD34(+) cells isolated after tr …
AMD3100 induced rapid mobilization of mouse and human HPCs and synergistically augmented G-CSF-induced mobilization of HPCs. ...AMD31 …
Modulation of Hematopoietic Chemokine Effects In Vitro and In Vivo by DPP-4/CD26.
Broxmeyer HE, Capitano M, Campbell TB, Hangoc G, Cooper S. Broxmeyer HE, et al. Among authors: hangoc g. Stem Cells Dev. 2016 Apr 15;25(8):575-85. doi: 10.1089/scd.2016.0026. Epub 2016 Mar 30. Stem Cells Dev. 2016. PMID: 26943017 Free PMC article.
Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.
Mantel CR, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Haas DM, Falah N, Kapur R, Pelus LM, Bardeesy N, Fitamant J, Ivan M, Kim KS, Broxmeyer HE. Mantel CR, et al. Among authors: hangoc g. Cell. 2015 Jun 18;161(7):1553-65. doi: 10.1016/j.cell.2015.04.054. Epub 2015 Jun 11. Cell. 2015. PMID: 26073944 Free PMC article.
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