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AhR- and ERK-dependent pathways function synergistically to mediate 2,3,7,8-tetrachlorodibenzo-p-dioxin suppression of peroxisome proliferator-activated receptor-gamma1 expression and subsequent adipocyte differentiation.
Hanlon PR, Ganem LG, Cho YC, Yamamoto M, Jefcoate CR. Hanlon PR, et al. Toxicol Appl Pharmacol. 2003 May 15;189(1):11-27. doi: 10.1016/s0041-008x(03)00083-8. Toxicol Appl Pharmacol. 2003. PMID: 12758056
Microarray analysis of early adipogenesis in C3H10T1/2 cells: cooperative inhibitory effects of growth factors and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Hanlon PR, Cimafranca MA, Liu X, Cho YC, Jefcoate CR. Hanlon PR, et al. Toxicol Appl Pharmacol. 2005 Aug 22;207(1):39-58. doi: 10.1016/j.taap.2004.12.004. Toxicol Appl Pharmacol. 2005. PMID: 16054899
Differentiation of pluripotent C3H10T1/2 cells rapidly elevates CYP1B1 through a novel process that overcomes a loss of Ah Receptor.
Cho YC, Zheng W, Yamamoto M, Liu X, Hanlon PR, Jefcoate CR. Cho YC, et al. Among authors: hanlon pr. Arch Biochem Biophys. 2005 Jul 15;439(2):139-53. doi: 10.1016/j.abb.2005.04.025. Arch Biochem Biophys. 2005. PMID: 15967407
Identification of novel TCDD-regulated genes by microarray analysis.
Hanlon PR, Zheng W, Ko AY, Jefcoate CR. Hanlon PR, et al. Toxicol Appl Pharmacol. 2005 Feb 1;202(3):215-28. doi: 10.1016/j.taap.2004.06.018. Toxicol Appl Pharmacol. 2005. PMID: 15667827
TCDD administration after the pro-adipogenic differentiation stimulus inhibits PPARgamma through a MEK-dependent process but less effectively suppresses adipogenesis.
Cimafranca MA, Hanlon PR, Jefcoate CR. Cimafranca MA, et al. Toxicol Appl Pharmacol. 2004 Apr 1;196(1):156-68. doi: 10.1016/j.taap.2003.12.005. Toxicol Appl Pharmacol. 2004. PMID: 15050417
Effects of inorganic HgCl2 on adipogenesis.
Barnes DM, Hanlon PR, Kircher EA. Barnes DM, et al. Toxicol Sci. 2003 Oct;75(2):368-77. doi: 10.1093/toxsci/kfg195. Epub 2003 Jul 25. Toxicol Sci. 2003. PMID: 12883084
Acute hemorrhagic myocardial necrosis and sudden death of rats exposed to a combination of ephedrine and caffeine.
Nyska A, Murphy E, Foley JF, Collins BJ, Petranka J, Howden R, Hanlon P, Dunnick JK. Nyska A, et al. Toxicol Sci. 2005 Feb;83(2):388-96. doi: 10.1093/toxsci/kfi034. Epub 2004 Nov 10. Toxicol Sci. 2005. PMID: 15537744
Spanish black radish (Raphanus sativus L. Var. niger) diet enhances clearance of DMBA and diminishes toxic effects on bone marrow progenitor cells.
N'jai AU, Kemp MQ, Metzger BT, Hanlon PR, Robbins M, Czuyprynski C, Barnes DM. N'jai AU, et al. Among authors: hanlon pr. Nutr Cancer. 2012;64(7):1038-48. doi: 10.1080/01635581.2012.714831. Nutr Cancer. 2012. PMID: 23061907
Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats.
Howden R, Hanlon PR, Petranka JG, Kleeberger S, Bucher J, Dunnick J, Nyska A, Murphy E. Howden R, et al. Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2219-24. doi: 10.1152/ajpheart.01164.2004. Epub 2005 Jan 14. Am J Physiol Heart Circ Physiol. 2005. PMID: 15653753
Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury.
Wright GL, Hanlon P, Amin K, Steenbergen C, Murphy E, Arcasoy MO. Wright GL, et al. FASEB J. 2004 Jun;18(9):1031-3. doi: 10.1096/fj.03-1289fje. Epub 2004 Apr 1. FASEB J. 2004. PMID: 15059965
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