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Massively parallel assessment of human variants with base editor screens.
Hanna RE, Hegde M, Fagre CR, DeWeirdt PC, Sangree AK, Szegletes Z, Griffith A, Feeley MN, Sanson KR, Baidi Y, Koblan LW, Liu DR, Neal JT, Doench JG. Hanna RE, et al. Cell. 2021 Feb 18;184(4):1064-1080.e20. doi: 10.1016/j.cell.2021.01.012. Cell. 2021. PMID: 33606977 Free article.
A case of mistaken identity.
Hanna RE, Doench JG. Hanna RE, et al. Nat Biotechnol. 2018 Sep 6;36(9):802-804. doi: 10.1038/nbt.4208. Nat Biotechnol. 2018. PMID: 30188534 No abstract available.
Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities.
Sanson KR, Hanna RE, Hegde M, Donovan KF, Strand C, Sullender ME, Vaimberg EW, Goodale A, Root DE, Piccioni F, Doench JG. Sanson KR, et al. Among authors: hanna re. Nat Commun. 2018 Dec 21;9(1):5416. doi: 10.1038/s41467-018-07901-8. Nat Commun. 2018. PMID: 30575746 Free PMC article.
Design and analysis of CRISPR-Cas experiments.
Hanna RE, Doench JG. Hanna RE, et al. Nat Biotechnol. 2020 Jul;38(7):813-823. doi: 10.1038/s41587-020-0490-7. Epub 2020 Apr 13. Nat Biotechnol. 2020. PMID: 32284587 Review.
Optimization of AsCas12a for combinatorial genetic screens in human cells.
DeWeirdt PC, Sanson KR, Sangree AK, Hegde M, Hanna RE, Feeley MN, Griffith AL, Teng T, Borys SM, Strand C, Joung JK, Kleinstiver BP, Pan X, Huang A, Doench JG. DeWeirdt PC, et al. Among authors: hanna re. Nat Biotechnol. 2021 Jan;39(1):94-104. doi: 10.1038/s41587-020-0600-6. Epub 2020 Jul 13. Nat Biotechnol. 2021. PMID: 32661438 Free PMC article.
Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection.
Wei J, Alfajaro MM, Hanna RE, DeWeirdt PC, Strine MS, Lu-Culligan WJ, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Gasque V, de Miguel F, Chen H, Oguntuyo K, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach B, Politi K, van Dijk D, Simon MD, Yan Q, Doench JG, Wilen CB. Wei J, et al. Among authors: hanna re. bioRxiv [Preprint]. 2020 Jun 17:2020.06.16.155101. doi: 10.1101/2020.06.16.155101. bioRxiv. 2020. PMID: 32869025 Free PMC article. Updated. Preprint.
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Wei J, Alfajaro MM, DeWeirdt PC, Hanna RE, Lu-Culligan WJ, Cai WL, Strine MS, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Ravindra NG, Gasque V, de Miguel FJ, Patil A, Chen H, Oguntuyo KY, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach BD, Politi K, van Dijk D, Kadoch C, Simon MD, Yan Q, Doench JG, Wilen CB. Wei J, et al. Among authors: hanna re. Cell. 2021 Jan 7;184(1):76-91.e13. doi: 10.1016/j.cell.2020.10.028. Epub 2020 Oct 20. Cell. 2021. PMID: 33147444 Free PMC article.
105 results