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Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models.
Hvid H, Brand CL, Hummelshøj T, Jensen S, Bouman SD, Bowler A, Poulsen BR, Tiainen P, Åkertröm T, Demozay D, Hoeg-Jensen T, Ingvorsen C, Pedersen TÅ, McGuire J, Egebjerg T, Cappelen KA, Eliasen IP, Hansen BF, Hennen S, Stidsen CE, Olsen GS, Roed NK. Hvid H, et al. Among authors: hansen bf. Diabetologia. 2023 Feb;66(2):376-389. doi: 10.1007/s00125-022-05828-w. Epub 2022 Nov 21. Diabetologia. 2023. PMID: 36404376 Free PMC article.
Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing.
Nishimura E, Pridal L, Glendorf T, Hansen BF, Hubálek F, Kjeldsen T, Kristensen NR, Lützen A, Lyby K, Madsen P, Pedersen TÅ, Ribel-Madsen R, Stidsen CE, Haahr H. Nishimura E, et al. Among authors: hansen bf. BMJ Open Diabetes Res Care. 2021 Aug;9(1):e002301. doi: 10.1136/bmjdrc-2021-002301. BMJ Open Diabetes Res Care. 2021. PMID: 34413118 Free PMC article. Clinical Trial.
Author Correction: Molecular engineering of safe and efficacious oral basal insulin.
Hubálek F, Refsgaard HHF, Gram-Nielsen S, Madsen P, Nishimura E, Münzel M, Brand CL, Stidsen CE, Claussen CH, Wulff EM, Pridal L, Ribel U, Kildegaard J, Porsgaard T, Johansson E, Steensgaard DB, Hovgaard L, Glendorf T, Hansen BF, Jensen MK, Nielsen PK, Ludvigsen S, Rugh S, Garibay PW, Moore MC, Cherrington AD, Kjeldsen T. Hubálek F, et al. Among authors: hansen bf. Nat Commun. 2020 Aug 20;11(1):4232. doi: 10.1038/s41467-020-18106-3. Nat Commun. 2020. PMID: 34244486 Free PMC article. No abstract available.
Molecular engineering of safe and efficacious oral basal insulin.
Hubálek F, Refsgaard HHF, Gram-Nielsen S, Madsen P, Nishimura E, Münzel M, Brand CL, Stidsen CE, Claussen CH, Wulff EM, Pridal L, Ribel U, Kildegaard J, Porsgaard T, Johansson E, Steensgaard DB, Hovgaard L, Glendorf T, Hansen BF, Jensen MK, Nielsen PK, Ludvigsen S, Rugh S, Garibay PW, Moore MC, Cherrington AD, Kjeldsen T. Hubálek F, et al. Among authors: hansen bf. Nat Commun. 2020 Jul 27;11(1):3746. doi: 10.1038/s41467-020-17487-9. Nat Commun. 2020. PMID: 32719315 Free PMC article.
Intraintestinal and Parenteral Administration of an Insulin Analogue Leads to Comparable Activation of Signaling Downstream of the Insulin Receptor in the Small Intestine.
Hvid H, Kildegaard J, Kristensen K, Porsgaard T, Jørgensen MS, Ballarín-González B, Ahnfelt-Rønne J, Hansen BF, Nishimura E. Hvid H, et al. Among authors: hansen bf. J Diabetes Sci Technol. 2020 Jan;14(1):112-119. doi: 10.1177/1932296819855075. Epub 2019 Jun 12. J Diabetes Sci Technol. 2020. PMID: 31189343 Free PMC article.
184 results