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21 results
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Turning on the off switch: regulation of anti-viral T cell responses in the liver by the PD-1/PD-L1 pathway.
Grakoui A, John Wherry E, Hanson HL, Walker C, Ahmed R. Grakoui A, et al. Among authors: hanson hl. J Hepatol. 2006 Oct;45(4):468-72. doi: 10.1016/j.jhep.2006.07.009. Epub 2006 Jul 25. J Hepatol. 2006. PMID: 16901572 Review. No abstract available.
Unraveling the role of PD-1/PD-L interactions in persistent hepatotropic infections: potential for therapeutic application?
Radziewicz H, Hanson HL, Ahmed R, Grakoui A. Radziewicz H, et al. Among authors: hanson hl. Gastroenterology. 2008 Jun;134(7):2168-71. doi: 10.1053/j.gastro.2008.04.012. Epub 2008 May 16. Gastroenterology. 2008. PMID: 18486616 No abstract available.
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression.
Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, Hanson HL, Steinberg JP, Masopust D, Wherry EJ, Altman JD, Rouse BT, Freeman GJ, Ahmed R, Grakoui A. Radziewicz H, et al. Among authors: hanson hl. J Virol. 2007 Mar;81(6):2545-53. doi: 10.1128/JVI.02021-06. Epub 2006 Dec 20. J Virol. 2007. PMID: 17182670 Free PMC article.
Impaired hepatitis C virus (HCV)-specific effector CD8+ T cells undergo massive apoptosis in the peripheral blood during acute HCV infection and in the liver during the chronic phase of infection.
Radziewicz H, Ibegbu CC, Hon H, Osborn MK, Obideen K, Wehbi M, Freeman GJ, Lennox JL, Workowski KA, Hanson HL, Grakoui A. Radziewicz H, et al. Among authors: hanson hl. J Virol. 2008 Oct;82(20):9808-22. doi: 10.1128/JVI.01075-08. Epub 2008 Jul 30. J Virol. 2008. PMID: 18667503 Free PMC article.
Stable cytotoxic T cell escape mutation in hepatitis C virus is linked to maintenance of viral fitness.
Uebelhoer L, Han JH, Callendret B, Mateu G, Shoukry NH, Hanson HL, Rice CM, Walker CM, Grakoui A. Uebelhoer L, et al. Among authors: hanson hl. PLoS Pathog. 2008 Sep 5;4(9):e1000143. doi: 10.1371/journal.ppat.1000143. PLoS Pathog. 2008. PMID: 18773115 Free PMC article.
CD4-directed peptide vaccination augments an antitumor response, but efficacy is limited by the number of CD8+ T cell precursors.
Hanson HL, Kang SS, Norian LA, Matsui K, O'Mara LA, Allen PM. Hanson HL, et al. J Immunol. 2004 Apr 1;172(7):4215-24. doi: 10.4049/jimmunol.172.7.4215. J Immunol. 2004. PMID: 15034034
Eradication of established tumors by CD8+ T cell adoptive immunotherapy.
Hanson HL, Donermeyer DL, Ikeda H, White JM, Shankaran V, Old LJ, Shiku H, Schreiber RD, Allen PM. Hanson HL, et al. Immunity. 2000 Aug;13(2):265-76. doi: 10.1016/s1074-7613(00)00026-1. Immunity. 2000. PMID: 10981969
Beta cell apoptosis in T cell-mediated autoimmune diabetes.
Kurrer MO, Pakala SV, Hanson HL, Katz JD. Kurrer MO, et al. Among authors: hanson hl. Proc Natl Acad Sci U S A. 1997 Jan 7;94(1):213-8. doi: 10.1073/pnas.94.1.213. Proc Natl Acad Sci U S A. 1997. PMID: 8990188 Free PMC article.
Class I-restricted cytotoxic T cell recognition of split peptide ligands.
Gillanders WE, Hanson HL, Rubocki RJ, Hansen TH, Connolly JM. Gillanders WE, et al. Among authors: hanson hl. Int Immunol. 1997 Jan;9(1):81-9. doi: 10.1093/intimm/9.1.81. Int Immunol. 1997. PMID: 9043950
HCV persistence and immune evasion in the absence of memory T cell help.
Grakoui A, Shoukry NH, Woollard DJ, Han JH, Hanson HL, Ghrayeb J, Murthy KK, Rice CM, Walker CM. Grakoui A, et al. Among authors: hanson hl. Science. 2003 Oct 24;302(5645):659-62. doi: 10.1126/science.1088774. Science. 2003. PMID: 14576438
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