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Pharmacological characterization of N-tert-butyl-N'-[2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl]urea (BM-573), a novel thromboxane A2 receptor antagonist and thromboxane synthase inhibitor in a rat model of arterial thrombosis and its effects on bleeding time.
Dogné JM, Hanson J, de Leval X, Kolh P, Tchana-Sato V, de Leval L, Rolin S, Ghuysen A, Segers P, Lambermont B, Masereel B, Pirotte B. Dogné JM, et al. Among authors: hanson j. J Pharmacol Exp Ther. 2004 May;309(2):498-505. doi: 10.1124/jpet.103.063610. Epub 2004 Jan 23. J Pharmacol Exp Ther. 2004. PMID: 14742735
Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism.
Ghuysen A, Lambermont B, Dogné JM, Kolh P, Tchana-Sato V, Morimont P, Magis D, Hanson J, Segers P, D'Orio V. Ghuysen A, et al. Among authors: hanson j. J Pharmacol Exp Ther. 2004 Sep;310(3):964-72. doi: 10.1124/jpet.104.066852. Epub 2004 Apr 30. J Pharmacol Exp Ther. 2004. PMID: 15121765
In vitro and in vivo pharmacological characterization of BM-613 [N-n-pentyl-N'-[2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl]urea], a novel dual thromboxane synthase inhibitor and thromboxane receptor antagonist.
Hanson J, Rolin S, Reynaud D, Qiao N, Kelley LP, Reid HM, Valentin F, Tippins J, Kinsella BT, Masereel B, Pace-Asciak C, Pirotte B, Dogné JM. Hanson J, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):293-301. doi: 10.1124/jpet.104.079301. Epub 2004 Dec 30. J Pharmacol Exp Ther. 2005. PMID: 15626721
Forskolin-free cAMP assay for Gi-coupled receptors.
Gilissen J, Geubelle P, Dupuis N, Laschet C, Pirotte B, Hanson J. Gilissen J, et al. Among authors: hanson j. Biochem Pharmacol. 2015 Dec 1;98(3):381-91. doi: 10.1016/j.bcp.2015.09.010. Epub 2015 Sep 16. Biochem Pharmacol. 2015. PMID: 26386312
Insight into SUCNR1 (GPR91) structure and function.
Gilissen J, Jouret F, Pirotte B, Hanson J. Gilissen J, et al. Among authors: hanson j. Pharmacol Ther. 2016 Mar;159:56-65. doi: 10.1016/j.pharmthera.2016.01.008. Epub 2016 Jan 22. Pharmacol Ther. 2016. PMID: 26808164 Review.
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