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Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways.
Enuka Y, Hanukoglu I, Edelheit O, Vaknine H, Hanukoglu A. Enuka Y, et al. Histochem Cell Biol. 2012 Mar;137(3):339-53. doi: 10.1007/s00418-011-0904-1. Epub 2011 Dec 30. Histochem Cell Biol. 2012. PMID: 22207244
Gene structure of the human amiloride-sensitive epithelial sodium channel beta subunit.
Saxena A, Hanukoglu I, Strautnieks SS, Thompson RJ, Gardiner RM, Hanukoglu A. Saxena A, et al. Biochem Biophys Res Commun. 1998 Nov 9;252(1):208-13. doi: 10.1006/bbrc.1998.9625. Biochem Biophys Res Commun. 1998. PMID: 9813171
Novel mutations responsible for autosomal recessive multisystem pseudohypoaldosteronism and sequence variants in epithelial sodium channel alpha-, beta-, and gamma-subunit genes.
Saxena A, Hanukoglu I, Saxena D, Thompson RJ, Gardiner RM, Hanukoglu A. Saxena A, et al. J Clin Endocrinol Metab. 2002 Jul;87(7):3344-50. doi: 10.1210/jcem.87.7.8674. J Clin Endocrinol Metab. 2002. PMID: 12107247
Novel mutations in epithelial sodium channel (ENaC) subunit genes and phenotypic expression of multisystem pseudohypoaldosteronism.
Edelheit O, Hanukoglu I, Gizewska M, Kandemir N, Tenenbaum-Rakover Y, Yurdakök M, Zajaczek S, Hanukoglu A. Edelheit O, et al. Clin Endocrinol (Oxf). 2005 May;62(5):547-53. doi: 10.1111/j.1365-2265.2005.02255.x. Clin Endocrinol (Oxf). 2005. PMID: 15853823 Review.
Renin-aldosterone response, urinary Na/K ratio and growth in pseudohypoaldosteronism patients with mutations in epithelial sodium channel (ENaC) subunit genes.
Hanukoglu A, Edelheit O, Shriki Y, Gizewska M, Dascal N, Hanukoglu I. Hanukoglu A, et al. J Steroid Biochem Mol Biol. 2008 Sep;111(3-5):268-74. doi: 10.1016/j.jsbmb.2008.06.013. Epub 2008 Jun 26. J Steroid Biochem Mol Biol. 2008. PMID: 18634878
Truncated beta epithelial sodium channel (ENaC) subunits responsible for multi-system pseudohypoaldosteronism support partial activity of ENaC.
Edelheit O, Hanukoglu I, Shriki Y, Tfilin M, Dascal N, Gillis D, Hanukoglu A. Edelheit O, et al. J Steroid Biochem Mol Biol. 2010 Mar;119(1-2):84-8. doi: 10.1016/j.jsbmb.2010.01.002. Epub 2010 Jan 12. J Steroid Biochem Mol Biol. 2010. PMID: 20064610
Identification of the roles of conserved charged residues in the extracellular domain of an epithelial sodium channel (ENaC) subunit by alanine mutagenesis.
Edelheit O, Hanukoglu I, Dascal N, Hanukoglu A. Edelheit O, et al. Am J Physiol Renal Physiol. 2011 Apr;300(4):F887-97. doi: 10.1152/ajprenal.00648.2010. Epub 2011 Jan 5. Am J Physiol Renal Physiol. 2011. PMID: 21209000
Conserved charged residues at the surface and interface of epithelial sodium channel subunits--roles in cell surface expression and the sodium self-inhibition response.
Edelheit O, Ben-Shahar R, Dascal N, Hanukoglu A, Hanukoglu I. Edelheit O, et al. FEBS J. 2014 Apr;281(8):2097-111. doi: 10.1111/febs.12765. Epub 2014 Mar 17. FEBS J. 2014. PMID: 24571549
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