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Possible involvement of RasGRP4 in leukemogenesis.
Watanabe-Okochi N, Oki T, Komeno Y, Kato N, Yuji K, Ono R, Harada Y, Harada H, Hayashi Y, Nakajima H, Nosaka T, Kitaura J, Kitamura T. Watanabe-Okochi N, et al. Among authors: harada h, harada y. Int J Hematol. 2009 May;89(4):470-481. doi: 10.1007/s12185-009-0299-0. Epub 2009 Apr 7. Int J Hematol. 2009. PMID: 19350351
Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis.
Uchida T, Kitaura J, Nakahara F, Togami K, Inoue D, Maehara A, Nishimura K, Kawabata KC, Doki N, Kakihana K, Yoshioka K, Izawa K, Oki T, Sada A, Harada Y, Ohashi K, Katayama Y, Matsui T, Harada H, Kitamura T. Uchida T, et al. Among authors: harada h, harada y. Exp Hematol. 2014 May;42(5):369-379.e3. doi: 10.1016/j.exphem.2014.01.009. Epub 2014 Jan 31. Exp Hematol. 2014. PMID: 24486648 Clinical Trial.
A C-terminal mutant of CCAAT-enhancer-binding protein α (C/EBPα-Cm) downregulates Csf1r, a potent accelerator in the progression of acute myeloid leukemia with C/EBPα-Cm.
Togami K, Kitaura J, Uchida T, Inoue D, Nishimura K, Kawabata KC, Nagase R, Horikawa S, Izawa K, Fukuyama T, Nakahara F, Oki T, Harada Y, Harada H, Aburatani H, Kitamura T. Togami K, et al. Among authors: harada h, harada y. Exp Hematol. 2015 Apr;43(4):300-8.e1. doi: 10.1016/j.exphem.2014.11.011. Epub 2014 Dec 20. Exp Hematol. 2015. PMID: 25534203
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