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A simple PCR method for rapid genotype analysis of the TH-MYCN transgenic mouse.
Haraguchi S, Nakagawara A. Haraguchi S, et al. PLoS One. 2009 Sep 4;4(9):e6902. doi: 10.1371/journal.pone.0006902. PLoS One. 2009. PMID: 19730731 Free PMC article.
NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas.
Suenaga Y, Islam SM, Alagu J, Kaneko Y, Kato M, Tanaka Y, Kawana H, Hossain S, Matsumoto D, Yamamoto M, Shoji W, Itami M, Shibata T, Nakamura Y, Ohira M, Haraguchi S, Takatori A, Nakagawara A. Suenaga Y, et al. PLoS Genet. 2014 Jan;10(1):e1003996. doi: 10.1371/journal.pgen.1003996. Epub 2014 Jan 2. PLoS Genet. 2014. PMID: 24391509 Free PMC article.
Muscle atrophy and motor neuron degeneration in human NEDL1 transgenic mice.
Zhang L, Haraguchi S, Koda T, Hashimoto K, Nakagawara A. Zhang L, et al. J Biomed Biotechnol. 2011;2011:831092. doi: 10.1155/2011/831092. Epub 2010 Oct 3. J Biomed Biotechnol. 2011. PMID: 20976258 Free PMC article.
Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression.
Zhu Y, Li Y, Haraguchi S, Yu M, Ohira M, Ozaki T, Nakagawa A, Ushijima T, Isogai E, Koseki H, Nakamura Y, Kong C, Mehlen P, Arakawa H, Nakagawara A. Zhu Y, et al. J Clin Invest. 2013 Jul;123(7):2935-47. doi: 10.1172/JCI65988. Epub 2013 Jun 17. J Clin Invest. 2013. PMID: 23778138 Free PMC article.
Oncogenic Lmo3 cooperates with Hen2 to induce hydrocephalus in mice.
Isogai E, Okumura K, Saito M, Yoshizawa Y, Itoh K, Tando S, Ohira M, Haraguchi S, Nakagawara A, Fushiki S, Nagase H, Wakabayashi Y. Isogai E, et al. Exp Anim. 2015;64(4):407-14. doi: 10.1538/expanim.15-0026. Epub 2015 Jul 6. Exp Anim. 2015. PMID: 26156403 Free PMC article.
A novel apoptotic pathway induced by the drs tumor suppressor gene.
Tambe Y, Isono T, Haraguchi S, Yoshioka-Yamashita A, Yutsudo M, Inoue H. Tambe Y, et al. Oncogene. 2004 Apr 15;23(17):2977-87. doi: 10.1038/sj.onc.1207419. Oncogene. 2004. PMID: 15021917
Furthermore, we found that the Drs protein can interact with ASY/Nogo-B/RTN-x(S), an apoptosis-inducing protein localized in the endoplasmic reticulum, and that coexpression of these genes increased the efficiency of apoptosis. These results indicated that Drs induces apop …
Furthermore, we found that the Drs protein can interact with ASY/Nogo-B/RTN-x(S), an apoptosis-inducing protein localized in the endo …
Tumor prone phenotype of mice deficient in a novel apoptosis-inducing gene, drs.
Tambe Y, Yoshioka-Yamashita A, Mukaisho K, Haraguchi S, Chano T, Isono T, Kawai T, Suzuki Y, Kushima R, Hattori T, Goto M, Yamada S, Kiso M, Saga Y, Inoue H. Tambe Y, et al. Carcinogenesis. 2007 Apr;28(4):777-84. doi: 10.1093/carcin/bgl211. Epub 2006 Nov 4. Carcinogenesis. 2007. PMID: 17088259
Previously, we found that Drs protein associates with ASY/Nogo-B/RTN-x(S), an apoptosis-inducing protein in the endoplasmic reticulum, and sequentially activates caspases to induce apoptosis in human cancer cells without involvement of the mitochondria. ...
Previously, we found that Drs protein associates with ASY/Nogo-B/RTN-x(S), an apoptosis-inducing protein in the endoplasmic reticulum …
Downregulation of histone methyltransferase genes SUV39H1 and SUV39H2 increases telomere length in embryonic stem-like cells and embryonic fibroblasts in pigs.
Dang-Nguyen TQ, Haraguchi S, Furusawa T, Somfai T, Kaneda M, Watanabe S, Akagi S, Kikuchi K, Tajima A, Nagai T. Dang-Nguyen TQ, et al. J Reprod Dev. 2013;59(1):27-32. doi: 10.1262/jrd.2012-118. Epub 2012 Sep 28. J Reprod Dev. 2013. PMID: 23018532 Free PMC article.
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