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Acute exposure to streptozotocin but not human proinflammatory cytokines impairs neonatal porcine islet insulin secretion in vitro but not in vivo.
Harb G, Toreson J, Dufour J, Korbutt G. Harb G, et al. Xenotransplantation. 2007 Nov;14(6):580-90. doi: 10.1111/j.1399-3089.2007.00427.x. Xenotransplantation. 2007. PMID: 17991146
Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
Shen W, Taylor B, Jin Q, Nguyen-Tran V, Meeusen S, Zhang YQ, Kamireddy A, Swafford A, Powers AF, Walker J, Lamb J, Bursalaya B, DiDonato M, Harb G, Qiu M, Filippi CM, Deaton L, Turk CN, Suarez-Pinzon WL, Liu Y, Hao X, Mo T, Yan S, Li J, Herman AE, Hering BJ, Wu T, Martin Seidel H, McNamara P, Glynne R, Laffitte B. Shen W, et al. Among authors: harb g. Nat Commun. 2015 Oct 26;6:8372. doi: 10.1038/ncomms9372. Nat Commun. 2015. PMID: 26496802 Free PMC article.
Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels.
Webster NJ, Searle GJ, Lam PP, Huang YC, Riedel MJ, Harb G, Gaisano HY, Holt A, Light PE. Webster NJ, et al. Among authors: harb g. Endocrinology. 2008 Jul;149(7):3679-87. doi: 10.1210/en.2007-1138. Epub 2008 Mar 27. Endocrinology. 2008. PMID: 18372336
Prolonged survival of microencapsulated neonatal porcine islet xenografts in immune-competent mice without antirejection therapy.
Kobayashi T, Arefanian H, Harb G, Tredget EB, Rajotte RV, Korbutt GS, Rayat GR. Kobayashi T, et al. Among authors: harb g. Cell Transplant. 2008;17(10-11):1243-56. doi: 10.3727/096368908787236602. Cell Transplant. 2008. PMID: 19181218
Marginal mass islet transplantation with autologous mesenchymal stem cells promotes long-term islet allograft survival and sustained normoglycemia.
Solari MG, Srinivasan S, Boumaza I, Unadkat J, Harb G, Garcia-Ocana A, Feili-Hariri M. Solari MG, et al. Among authors: harb g. J Autoimmun. 2009 Mar;32(2):116-24. doi: 10.1016/j.jaut.2009.01.003. Epub 2009 Feb 12. J Autoimmun. 2009. PMID: 19217258
Effect of prolonged in vitro exposure to high glucose on neonatal porcine pancreatic islets.
Harb G, Korbutt GS. Harb G, et al. J Endocrinol. 2006 Oct;191(1):37-44. doi: 10.1677/joe.1.06812. J Endocrinol. 2006. PMID: 17065387
Immune mechanisms associated with the rejection of encapsulated neonatal porcine islet xenografts.
Kobayashi T, Harb G, Rajotte RV, Korbutt GS, Mallett AG, Arefanian H, Mok D, Rayat GR. Kobayashi T, et al. Among authors: harb g. Xenotransplantation. 2006 Nov;13(6):547-59. doi: 10.1111/j.1399-3089.2006.00349.x. Xenotransplantation. 2006. PMID: 17059582
Prolonged survival of microencapsulated neonatal porcine islets in mice treated with a combination of anti-CD154 and anti-LFA-1 monoclonal antibodies.
Kobayashi T, Harb G, Rayat GR. Kobayashi T, et al. Among authors: harb g. Transplantation. 2005 Sep 27;80(6):821-7. doi: 10.1097/01.tp.0000173773.01811.88. Transplantation. 2005. PMID: 16210971
Survival of microencapsulated islets at 400 days posttransplantation in the omental pouch of NOD mice.
Kobayashi T, Aomatsu Y, Iwata H, Kin T, Kanehiro H, Hisanga M, Ko S, Nagao M, Harb G, Nakajima Y. Kobayashi T, et al. Among authors: harb g. Cell Transplant. 2006;15(4):359-65. doi: 10.3727/000000006783981954. Cell Transplant. 2006. PMID: 16898230
Ectopic expression of neurogenin 3 in neonatal pig pancreatic precursor cells induces (trans)differentiation to functional alpha cells.
Harb G, Heremans Y, Heimberg H, Korbutt GS. Harb G, et al. Diabetologia. 2006 Aug;49(8):1855-63. doi: 10.1007/s00125-006-0299-z. Epub 2006 May 31. Diabetologia. 2006. PMID: 16736130
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