TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection.
Reba SM, Li Q, Onwuzulike S, Nagy N, Fletcher S, Parker K, Shaw RJ, Umphred-Wilson K, Shukla S, Harding CV, Boom WH, Rojas RE.
Reba SM, et al. Among authors: harding cv.
Eur J Immunol. 2024 Mar 6:e2350715. doi: 10.1002/eji.202350715. Online ahead of print.
Eur J Immunol. 2024.
PMID: 38446066
To address TLR2 on T cells, we generated Tlr2(fl/fl) xCd4(cre/cre) mice, which lack expression of TLR2 on both CD4 and CD8 T cells, to study the in vivo role of TLR2 on T cells after aerosol infection with virulent Mtb. Deletion of TLR2 in CD4+ …
To address TLR2 on T cells, we generated Tlr2(fl/fl) xCd4(cre/cre) mice, which lack expression of TLR2 on both CD4 and …