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Antigen-specific human antibodies from mice comprising four distinct genetic modifications.
Lonberg N, Taylor LD, Harding FA, Trounstine M, Higgins KM, Schramm SR, Kuo CC, Mashayekh R, Wymore K, McCabe JG, et al. Lonberg N, et al. Nature. 1994 Apr 28;368(6474):856-9. doi: 10.1038/368856a0. Nature. 1994. PMID: 8159246
MHC restriction of T-cell proliferative responses in Xenopus.
Harding FA, Flajnik MF, Cohen N. Harding FA, et al. Dev Comp Immunol. 1993 Sep-Oct;17(5):425-37. doi: 10.1016/0145-305x(93)90034-n. Dev Comp Immunol. 1993. PMID: 7505753
High-avidity human IgG kappa monoclonal antibodies from a novel strain of minilocus transgenic mice.
Fishwild DM, O'Donnell SL, Bengoechea T, Hudson DV, Harding F, Bernhard SL, Jones D, Kay RM, Higgins KM, Schramm SR, Lonberg N. Fishwild DM, et al. Nat Biotechnol. 1996 Jul;14(7):845-51. doi: 10.1038/nbt0796-845. Nat Biotechnol. 1996. PMID: 9631008
Class switching in human immunoglobulin transgenic mice.
Harding FA, Lonberg N. Harding FA, et al. Ann N Y Acad Sci. 1995 Sep 29;764:536-46. doi: 10.1111/j.1749-6632.1995.tb55879.x. Ann N Y Acad Sci. 1995. PMID: 7486582
Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope.
Yeung VP, Chang J, Miller J, Barnett C, Stickler M, Harding FA. Yeung VP, et al. Among authors: harding fa. J Immunol. 2004 Jun 1;172(11):6658-65. doi: 10.4049/jimmunol.172.11.6658. J Immunol. 2004. PMID: 15153481 Free article.
Enhanced immunogenicity of a functional enzyme by T cell epitope modification.
Mucha JM, Stickler MM, Poulose AJ, Ganshaw G, Saldajeno M, Collier K, Huang MT, Harding FA. Mucha JM, et al. Among authors: harding fa. BMC Immunol. 2002;3:2. doi: 10.1186/1471-2172-3-2. Epub 2002 Jan 25. BMC Immunol. 2002. PMID: 11869454 Free PMC article.
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