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Properties of the novel herpes simplex virus type 1 origin binding protein, OBPC.
Baradaran K, Hardwicke MA, Dabrowski CE, Schaffer PA. Baradaran K, et al. J Virol. 1996 Aug;70(8):5673-9. doi: 10.1128/JVI.70.8.5673-5679.1996. J Virol. 1996. PMID: 8764087 Free PMC article.
The C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicing.
Sandri-Goldin RM, Hibbard MK, Hardwicke MA. Sandri-Goldin RM, et al. J Virol. 1995 Oct;69(10):6063-76. doi: 10.1128/JVI.69.10.6063-6076.1995. J Virol. 1995. PMID: 7666511 Free PMC article.
The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.
Hardwicke MA, Vaughan PJ, Sekulovich RE, O'Conner R, Sandri-Goldin RM. Hardwicke MA, et al. J Virol. 1989 Nov;63(11):4590-602. doi: 10.1128/JVI.63.11.4590-4602.1989. J Virol. 1989. PMID: 2552143 Free PMC article.
Mutations in the activation region of herpes simplex virus regulatory protein ICP27 can be trans dominant.
Smith IL, Sekulovich RE, Hardwicke MA, Sandri-Goldin RM. Smith IL, et al. J Virol. 1991 Jul;65(7):3656-66. doi: 10.1128/JVI.65.7.3656-3666.1991. J Virol. 1991. PMID: 1645788 Free PMC article.
Hardwicke, P. J. Vaughan, R. E. Sekulovich, R. O'Conner, and R. M. Sandri-Goldin, J. Virol. 63:4590-4602, 1989). In this study, we cotransfected ICP27 activator and repressor mutants along with wild-type ICP27 plasmid to determine whether these mutants could interfere with
Hardwicke, P. J. Vaughan, R. E. Sekulovich, R. O'Conner, and R. M. Sandri-Goldin, J. Virol. 63:4590-4602, 1989). In this study, we co
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