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3,121 results
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TREM2 and neurodegenerative disease.
Guerreiro R, Hardy J. Guerreiro R, et al. Among authors: hardy j. N Engl J Med. 2013 Oct 17;369(16):1569-70. doi: 10.1056/NEJMc1306509. N Engl J Med. 2013. PMID: 24143816 No abstract available.
Antiamyloid therapy for Alzheimer's disease--are we on the right road?
Karran E, Hardy J. Karran E, et al. Among authors: hardy j. N Engl J Med. 2014 Jan 23;370(4):377-8. doi: 10.1056/NEJMe1313943. N Engl J Med. 2014. PMID: 24450897 No abstract available.
Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease.
Heslegrave A, Heywood W, Paterson R, Magdalinou N, Svensson J, Johansson P, Öhrfelt A, Blennow K, Hardy J, Schott J, Mills K, Zetterberg H. Heslegrave A, et al. Among authors: hardy j. Mol Neurodegener. 2016 Jan 12;11:3. doi: 10.1186/s13024-016-0071-x. Mol Neurodegener. 2016. PMID: 26754172 Free PMC article.
Genetic variants in glutamate-, Aβ-, and tau-related pathways determine polygenic risk for Alzheimer's disease.
Lawingco T, Chaudhury S, Brookes KJ, Guetta-Baranes T, Guerreiro R, Bras J, Hardy J, Francis P, Thomas A, Belbin O, Morgan K. Lawingco T, et al. Among authors: hardy j. Neurobiol Aging. 2020 Nov 12:S0197-4580(20)30391-2. doi: 10.1016/j.neurobiolaging.2020.11.009. Online ahead of print. Neurobiol Aging. 2020. PMID: 33303219
Genetics of Alzheimer's disease.
Guerreiro R, Hardy J. Guerreiro R, et al. Among authors: hardy j. Neurotherapeutics. 2014 Oct;11(4):732-7. doi: 10.1007/s13311-014-0295-9. Neurotherapeutics. 2014. PMID: 25113539 Free PMC article. Review.
Alzheimer's disease: the amyloid cascade hypothesis.
Hardy JA, Higgins GA. Hardy JA, et al. Science. 1992 Apr 10;256(5054):184-5. doi: 10.1126/science.1566067. Science. 1992. PMID: 1566067 Review. No abstract available.
A new way APP mismetabolism can lead to Alzheimer's disease.
Hardy J, Guerreiro R. Hardy J, et al. EMBO Mol Med. 2011 May;3(5):247-8. doi: 10.1002/emmm.201100139. Epub 2011 Apr 27. EMBO Mol Med. 2011. PMID: 21523909 Free PMC article. No abstract available.
Membrane damage is at the core of Alzheimer's disease.
Hardy J. Hardy J. Lancet Neurol. 2017 May;16(5):342. doi: 10.1016/S1474-4422(17)30091-1. Lancet Neurol. 2017. PMID: 28414646 No abstract available.
Amyloid precursor protein gene mutation in early-onset Alzheimer's disease.
van Duijn CM, Hendriks L, Cruts M, Hardy JA, Hofman A, Van Broeckhoven C. van Duijn CM, et al. Among authors: hardy ja. Lancet. 1991 Apr 20;337(8747):978. doi: 10.1016/0140-6736(91)91611-w. Lancet. 1991. PMID: 1678057 No abstract available.
Twenty years of Alzheimer's disease-causing mutations.
Goate A, Hardy J. Goate A, et al. Among authors: hardy j. J Neurochem. 2012 Jan;120 Suppl 1:3-8. doi: 10.1111/j.1471-4159.2011.07575.x. Epub 2011 Nov 28. J Neurochem. 2012. PMID: 22122678 Review.
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