Hari M - Search Results

1

Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel.

Hari M, Yang H, Zeng C, Canizales M, Cabral F. Hari M, et al. Cell Motil Cytoskeleton. 2003 Sep;56(1):45-56. doi: 10.1002/cm.10132. Cell Motil Cytoskeleton. 2003. PMID: 12905530

2

Mutations in alpha- and beta-tubulin that stabilize microtubules and confer resistance to colcemid and vinblastine.

Hari M, Wang Y, Veeraraghavan S, Cabral F. Hari M, et al. Mol Cancer Ther. 2003 Jul;2(7):597-605. Mol Cancer Ther. 2003. PMID: 12883031

3

Paclitaxel resistance by random mutagenesis of α-tubulin.

Yin S, Zeng C, Hari M, Cabral F. Yin S, et al. Among authors: hari m. Cytoskeleton (Hoboken). 2013 Dec;70(12):849-62. doi: 10.1002/cm.21154. Epub 2013 Nov 15. Cytoskeleton (Hoboken). 2013. PMID: 24155014 Free article.

4

Random mutagenesis of β-tubulin defines a set of dispersed mutations that confer paclitaxel resistance.

Yin S, Zeng C, Hari M, Cabral F. Yin S, et al. Among authors: hari m. Pharm Res. 2012 Nov;29(11):2994-3006. doi: 10.1007/s11095-012-0794-5. Epub 2012 Jun 6. Pharm Res. 2012. PMID: 22669706

5

Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules.

Hari M, Loganzo F, Annable T, Tan X, Musto S, Morilla DB, Nettles JH, Snyder JP, Greenberger LM. Hari M, et al. Mol Cancer Ther. 2006 Feb;5(2):270-8. doi: 10.1158/1535-7163.MCT-05-0190. Mol Cancer Ther. 2006. PMID: 16505100

6

Two photoaffinity analogues of the tripeptide, hemiasterlin, exclusively label alpha-tubulin.

Nunes M, Kaplan J, Wooters J, Hari M, Minnick AA Jr, May MK, Shi C, Musto S, Beyer C, Krishnamurthy G, Qiu Y, Loganzo F, Ayral-Kaloustian S, Zask A, Greenberger LM. Nunes M, et al. Among authors: hari m. Biochemistry. 2005 May 10;44(18):6844-57. doi: 10.1021/bi0474766. Biochemistry. 2005. PMID: 15865430

7

Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.

Loganzo F, Hari M, Annable T, Tan X, Morilla DB, Musto S, Zask A, Kaplan J, Minnick AA Jr, May MK, Ayral-Kaloustian S, Poruchynsky MS, Fojo T, Greenberger LM. Loganzo F, et al. Among authors: hari m. Mol Cancer Ther. 2004 Oct;3(10):1319-27. Mol Cancer Ther. 2004. PMID: 15486199

8

HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.

Loganzo F, Discafani CM, Annable T, Beyer C, Musto S, Hari M, Tan X, Hardy C, Hernandez R, Baxter M, Singanallore T, Khafizova G, Poruchynsky MS, Fojo T, Nieman JA, Ayral-Kaloustian S, Zask A, Andersen RJ, Greenberger LM. Loganzo F, et al. Among authors: hari m. Cancer Res. 2003 Apr 15;63(8):1838-45. Cancer Res. 2003. PMID: 12702571

9

Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models.

Sampath D, Greenberger LM, Beyer C, Hari M, Liu H, Baxter M, Yang S, Rios C, Discafani C. Sampath D, et al. Among authors: hari m. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3459-69. doi: 10.1158/1078-0432.CCR-05-2349. Clin Cancer Res. 2006. PMID: 16740771

10

Level of Anxiety and Depression and Its Clinical and Sociodemographic Determinants among the Parents of Children with Cancer Undergoing Chemotherapy.

Srivastava S, Menon V, Kayal S, Hari M, Dubashi B. Srivastava S, et al. Among authors: hari m. J Neurosci Rural Pract. 2020 Oct;11(4):530-537. doi: 10.1055/s-0040-1713581. Epub 2020 Jul 2. J Neurosci Rural Pract. 2020. PMID: 33144787 Free PMC article.

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