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A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus.
Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16529-16534. doi: 10.1073/pnas.1904700116. Epub 2019 Jul 29.
Proc Natl Acad Sci U S A. 2019.
PMID: 31358625
Free PMC article.
Hijacking the Bacterial Circuitry of Biofilm Processes via Chemical "Hot-Wiring": An Under-explored Avenue for Therapeutic Development.
Wilt IK, Hari TPA, Wuest WM.
Wilt IK, et al. Among authors: hari tpa.
ACS Infect Dis. 2019 Jun 14;5(6):789-795. doi: 10.1021/acsinfecdis.9b00104. Epub 2019 Apr 19.
ACS Infect Dis. 2019.
PMID: 31001972
Free PMC article.
Item in Clipboard
The role of transcription in heterologous expression of polyketides in bacterial hosts.
Stevens DC, Hari TP, Boddy CN.
Stevens DC, et al.
Nat Prod Rep. 2013 Oct 11;30(11):1391-411. doi: 10.1039/c3np70060g.
Nat Prod Rep. 2013.
PMID: 24061690
Review.
Item in Clipboard
Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?
Horsman ME, Hari TP, Boddy CN.
Horsman ME, et al.
Nat Prod Rep. 2016 Feb;33(2):183-202. doi: 10.1039/c4np00148f.
Nat Prod Rep. 2016.
PMID: 25642666
Review.
Item in Clipboard
An evolutionary model encompassing substrate specificity and reactivity of type I polyketide synthase thioesterases.
Hari TP, Labana P, Boileau M, Boddy CN.
Hari TP, et al.
Chembiochem. 2014 Dec 15;15(18):2656-61. doi: 10.1002/cbic.201402475. Epub 2014 Oct 29.
Chembiochem. 2014.
PMID: 25354333
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Diastereoseletive Transannular Oxa-Conjugate Addition Generates the 2,6-cis-Disubstituted Tetrahydropyran of Neopeltolide.
Hari TP, Wilke BI, Davey JA, Boddy CN.
Hari TP, et al.
J Org Chem. 2016 Jan 15;81(2):415-23. doi: 10.1021/acs.joc.5b02014. Epub 2015 Dec 29.
J Org Chem. 2016.
PMID: 26675500
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