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The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination.
Hariharan IK, Carthew RW, Rubin GM. Hariharan IK, et al. Cell. 1991 Nov 15;67(4):717-22. doi: 10.1016/0092-8674(91)90066-8. Cell. 1991. PMID: 1934069
Cloning and characterization of a receptor-class phosphotyrosine phosphatase gene expressed on central nervous system axons in Drosophila melanogaster.
Hariharan IK, Chuang PT, Rubin GM. Hariharan IK, et al. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11266-70. doi: 10.1073/pnas.88.24.11266. Proc Natl Acad Sci U S A. 1991. PMID: 1662390 Free PMC article.
Uncoupling cell fate determination from patterned cell division in the Drosophila eye.
de Nooij JC, Hariharan IK. de Nooij JC, et al. Among authors: hariharan ik. Science. 1995 Nov 10;270(5238):983-5. doi: 10.1126/science.270.5238.983. Science. 1995. PMID: 7481802
Star is required for neuronal differentiation in the Drosophila retina and displays dosage-sensitive interactions with Ras1.
Heberlein U, Hariharan IK, Rubin GM. Heberlein U, et al. Among authors: hariharan ik. Dev Biol. 1993 Nov;160(1):51-63. doi: 10.1006/dbio.1993.1285. Dev Biol. 1993. PMID: 8224548
A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis.
de Nooij JC, Letendre MA, Hariharan IK. de Nooij JC, et al. Among authors: hariharan ik. Cell. 1996 Dec 27;87(7):1237-47. doi: 10.1016/s0092-8674(00)81819-x. Cell. 1996. PMID: 8980230
Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets deubiquitinating enzyme in Drosophila eye development.
Li Q, Hariharan IK, Chen F, Huang Y, Fischer JA. Li Q, et al. Among authors: hariharan ik. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12515-20. doi: 10.1073/pnas.94.23.12515. Proc Natl Acad Sci U S A. 1997. PMID: 9356481 Free PMC article.
Comparative genomics of the eukaryotes.
Rubin GM, Yandell MD, Wortman JR, Gabor Miklos GL, Nelson CR, Hariharan IK, Fortini ME, Li PW, Apweiler R, Fleischmann W, Cherry JM, Henikoff S, Skupski MP, Misra S, Ashburner M, Birney E, Boguski MS, Brody T, Brokstein P, Celniker SE, Chervitz SA, Coates D, Cravchik A, Gabrielian A, Galle RF, Gelbart WM, George RA, Goldstein LS, Gong F, Guan P, Harris NL, Hay BA, Hoskins RA, Li J, Li Z, Hynes RO, Jones SJ, Kuehl PM, Lemaitre B, Littleton JT, Morrison DK, Mungall C, O'Farrell PH, Pickeral OK, Shue C, Vosshall LB, Zhang J, Zhao Q, Zheng XH, Lewis S. Rubin GM, et al. Among authors: hariharan ik. Science. 2000 Mar 24;287(5461):2204-15. doi: 10.1126/science.287.5461.2204. Science. 2000. PMID: 10731134 Free PMC article.
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.
Tapon N, Ito N, Dickson BJ, Treisman JE, Hariharan IK. Tapon N, et al. Among authors: hariharan ik. Cell. 2001 May 4;105(3):345-55. doi: 10.1016/s0092-8674(01)00332-4. Cell. 2001. PMID: 11348591
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines.
Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber D, Hariharan IK. Tapon N, et al. Among authors: hariharan ik. Cell. 2002 Aug 23;110(4):467-78. doi: 10.1016/s0092-8674(02)00824-3. Cell. 2002. PMID: 12202036
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis.
Harvey KF, Pfleger CM, Hariharan IK. Harvey KF, et al. Among authors: hariharan ik. Cell. 2003 Aug 22;114(4):457-67. doi: 10.1016/s0092-8674(03)00557-9. Cell. 2003. PMID: 12941274
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