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Signaling for myocardial depression in hemorrhagic shock: roles of Toll-like receptor 4 and p55 TNF-alpha receptor.
Meng X, Ao L, Song Y, Raeburn CD, Fullerton DA, Harken AH. Meng X, et al. Am J Physiol Regul Integr Comp Physiol. 2005 Mar;288(3):R600-6. doi: 10.1152/ajpregu.00182.2004. Epub 2004 Oct 28. Am J Physiol Regul Integr Comp Physiol. 2005. PMID: 15514106
Hemorrhage-induced acute lung injury is TLR-4 dependent.
Barsness KA, Arcaroli J, Harken AH, Abraham E, Banerjee A, Reznikov L, McIntyre RC. Barsness KA, et al. Am J Physiol Regul Integr Comp Physiol. 2004 Sep;287(3):R592-9. doi: 10.1152/ajpregu.00412.2003. Epub 2004 Apr 8. Am J Physiol Regul Integr Comp Physiol. 2004. PMID: 15072965
On-pump coronary artery bypass surgery activates human myocardial NF-kappaB and increases TNF-alpha in the heart.
Meldrum DR, Partrick DA, Cleveland JC Jr, Shenkar R, Meldrum KK, Raiesdana A, Ayala A, Brown JW, Harken AH. Meldrum DR, et al. J Surg Res. 2003 Jun 15;112(2):175-9. doi: 10.1016/s0022-4804(03)00122-7. J Surg Res. 2003. PMID: 12888335
Ischemia alone is sufficient to induce TNF-alpha mRNA and peptide in the myocardium.
Shames BD, Barton HH, Reznikov LL, Cairns CB, Banerjee A, Harken AH, Meng X. Shames BD, et al. Shock. 2002 Feb;17(2):114-9. doi: 10.1097/00024382-200202000-00006. Shock. 2002. PMID: 11837786
Mechanisms of neutrophil-mediated tissue injury.
Anderson BO, Brown JM, Harken AH. Anderson BO, et al. J Surg Res. 1991 Aug;51(2):170-9. doi: 10.1016/0022-4804(91)90090-9. J Surg Res. 1991. PMID: 1650866 Review.
The two-event construct of postinjury multiple organ failure.
Moore EE, Moore FA, Harken AH, Johnson JL, Ciesla D, Banerjee A. Moore EE, et al. Shock. 2005 Dec;24 Suppl 1:71-4. doi: 10.1097/01.shk.0000191336.01036.fe. Shock. 2005. PMID: 16374376 Review. No abstract available.
Therapeutic implications of interleukin-10 in surgical disease.
Selzman CH, Shames BD, Miller SA, Pulido EJ, Meng X, McIntyre RC Jr, Harken AH. Selzman CH, et al. Shock. 1998 Nov;10(5):309-18. doi: 10.1097/00024382-199811000-00001. Shock. 1998. PMID: 9840644 Review.
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