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The role of ECMO in COVID-19: Can it provide rescue therapy in those who are critically ill?
Savarimuthu S, BinSaeid J, Harky A. Savarimuthu S, et al. J Card Surg. 2020 Jun;35(6):1298-1301. doi: 10.1111/jocs.14635. Epub 2020 May 22. J Card Surg. 2020. PMID: 32442347 Free PMC article. Review.
Where mechanical ventilation may not be enough, extracorporeal membrane oxygenation (ECMO) could play a role as a form of rescue therapy and may provide beneficial results in the hands of skilled clinicians in centers with experience of using ECMO appropriately in s …
Where mechanical ventilation may not be enough, extracorporeal membrane oxygenation (ECMO) could play a role as a form of resc …
Pathogenesis of large vessel vasculitis: Implications for disease classification and future therapies.
Harky A, Fok M, Balmforth D, Bashir M. Harky A, et al. Vasc Med. 2019 Feb;24(1):79-88. doi: 10.1177/1358863X18802989. Epub 2018 Oct 24. Vasc Med. 2019. PMID: 30355272 Review.
Despite being recognised over a century ago, the aetiology and pathogenesis of large vessel vasculitis (LVV) still remains elusive. ...In this review, the histological, genetic and immunopathological features of TA and GCA will be discussed and the evidence for a co …
Despite being recognised over a century ago, the aetiology and pathogenesis of large vessel vasculitis (LVV) still remains elusive. . …
Valve-Sparing Aortic Root Repair Compared to Composite Aortic Root Replacement: A Systematic Review and Meta-Analysis.
Harky A, Fok M, Froghi S, Bilal H, Bashir M. Harky A, et al. J Heart Valve Dis. 2017 Nov;26(6):632-638. J Heart Valve Dis. 2017. PMID: 30207112
BACKGROUND: Aortic root aneurysms represent a significant risk of morbidity and mortality. Composite root replacement is the preferred practice for repair, although recently valve-sparing replacement has become a popular alternative. ...METHODS: A systematic …
BACKGROUND: Aortic root aneurysms represent a significant risk of morbidity and mortality. Composite root replacement is the preferre …
Aortic arch aneurysm surgery: what is the gold standard temperature in the absence of randomized data?
Harky A, Bashir M, Mariscalco G. Harky A, et al. Gen Thorac Cardiovasc Surg. 2019 Jan;67(1):127-131. doi: 10.1007/s11748-017-0867-9. Epub 2017 Nov 16. Gen Thorac Cardiovasc Surg. 2019. PMID: 29147918 Review.
A recent consensus has emerged setting to define the temperature levels. In an attempt, this was aimed to establish a solid ground for future trials in aortic arch surgery. ...
A recent consensus has emerged setting to define the temperature levels. In an attempt, this was aimed to establish a solid gr
Varying Evidence on Deep Hypothermic Circulatory Arrest in Thoracic Aortic Aneurysm Surgery.
Gupta P, Harky A, Jahangeer S, Adams B, Bashir M. Gupta P, et al. Tex Heart Inst J. 2018 Apr 7;45(2):70-75. doi: 10.14503/THIJ-17-6364. eCollection 2018 Apr. Tex Heart Inst J. 2018. PMID: 29844738 Free PMC article. Review.
Open versus Endovascular Repair of Descending Thoracic Aortic Aneurysm Disease: A Systematic Review and Meta-analysis.
Harky A, Kai Chan JS, Ming Wong CH, Bashir M. Harky A, et al. Ann Vasc Surg. 2019 Jan;54:304-315.e5. doi: 10.1016/j.avsg.2018.05.043. Epub 2018 Aug 4. Ann Vasc Surg. 2019. PMID: 30081163
RESULTS: A total of 14,580 patients were analyzed in total of 13 articles, which were included in the synthesis of the meta-analysis. ...A long-term data and studies are required to give a better understanding of comparing these 2 techniques beyond 5 years of …
RESULTS: A total of 14,580 patients were analyzed in total of 13 articles, which were included in the synthesis of the meta-analysis. …
Stented Versus Stentless Aortic Valve Replacement in Patients With Small Aortic Root: A Systematic Review and Meta-Analysis.
Harky A, Wong CHM, Hof A, Froghi S, Ahmad MU, Howard C, Rimmer L, Bashir M. Harky A, et al. Innovations (Phila). 2018 Nov/Dec;13(6):404-416. doi: 10.1097/IMI.0000000000000569. Innovations (Phila). 2018. PMID: 30543577
RESULTS: A total of seven studies with a total of 965 patients fulfilled the inclusion criteria. There was no significant difference in preoperative baselines including mean age between both groups (P = 0.08), peak aortic valve gradient (P = 0.06), and effective ori …
RESULTS: A total of seven studies with a total of 965 patients fulfilled the inclusion criteria. There was no significant diff …
Management of aortic valve disease during pregnancy: A review.
Maskell P, Burgess M, MacCarthy-Ofosu B, Harky A. Maskell P, et al. J Card Surg. 2019 May;34(5):239-249. doi: 10.1111/jocs.14039. Epub 2019 Apr 1. J Card Surg. 2019. PMID: 30932245 Review.
In conclusion, the management of aortic valvulopathy in pregnancy is a challenging field with only a small amount of clinical experience and retrospective study supporting evidence-based decisions in this field. A greater understanding of the most recent adva …
In conclusion, the management of aortic valvulopathy in pregnancy is a challenging field with only a small amount of clinical …
Aortic valve repair or replacement in patients with aortic regurgitation: A systematic review and meta-analysis.
Wong CHM, Chan JSK, Sanli D, Rahimli R, Harky A. Wong CHM, et al. J Card Surg. 2019 Jun;34(6):377-384. doi: 10.1111/jocs.14032. Epub 2019 Apr 6. J Card Surg. 2019. PMID: 30953445
METHODS: A comprehensive literature search was undertaken among the four major databases (PubMed, Embase, Scopus, and Ovid) to identify all published data comparing clinical outcomes of aortic valve repair vs replacement. ...RESULTS: A total of 1071 patients were an …
METHODS: A comprehensive literature search was undertaken among the four major databases (PubMed, Embase, Scopus, and Ovid) to identi …
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