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Point mutational inactivation of the retinoblastoma antioncogene.
Horowitz JM, Yandell DW, Park SH, Canning S, Whyte P, Buchkovich K, Harlow E, Weinberg RA, Dryja TP. Horowitz JM, et al. Science. 1989 Feb 17;243(4893):937-40. doi: 10.1126/science.2521957. Science. 1989. PMID: 2521957
Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase.
Tsai LH, Harlow E, Meyerson M. Tsai LH, et al. Nature. 1991 Sep 12;353(6340):174-7. doi: 10.1038/353174a0. Nature. 1991. PMID: 1653904
., L-H.T. and E.H., manuscript submitted). To isolate the gene for p33, we have cloned several novel human cdc2-related genes. ...
., L-H.T. and E.H., manuscript submitted). To isolate the gene for p33, we have cloned several novel human cdc2-related genes. ...
Disruption of retinoblastoma protein family function by human papillomavirus type 16 E7 oncoprotein inhibits lens development in part through E2F-1.
McCaffrey J, Yamasaki L, Dyson NJ, Harlow E, Griep AE. McCaffrey J, et al. Mol Cell Biol. 1999 Sep;19(9):6458-68. doi: 10.1128/mcb.19.9.6458. Mol Cell Biol. 1999. PMID: 10454591 Free PMC article.
In vivo association of E2F and DP family proteins.
Wu CL, Zukerberg LR, Ngwu C, Harlow E, Lees JA. Wu CL, et al. Mol Cell Biol. 1995 May;15(5):2536-46. doi: 10.1128/mcb.15.5.2536. Mol Cell Biol. 1995. PMID: 7739537 Free PMC article.
Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs.
Zarkowska T, U S, Harlow E, Mittnacht S. Zarkowska T, et al. Oncogene. 1997 Jan 16;14(2):249-54. doi: 10.1038/sj.onc.1200824. Oncogene. 1997. PMID: 9010227
We provide evidence that this residue, serine 608 of pRB, is an authentic phosphorylation site that can be phosphorylated in vitro by cyclin A-CDK2 and cyclin D1-CDK4 kinases but not by cyclin E-CDK2 kinase or the mitogen activated kinase ERK2. ...
We provide evidence that this residue, serine 608 of pRB, is an authentic phosphorylation site that can be phosphorylated in vitro by cyclin …
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
Zhu L, van den Heuvel S, Helin K, Fattaey A, Ewen M, Livingston D, Dyson N, Harlow E. Zhu L, et al. Genes Dev. 1993 Jul;7(7A):1111-25. doi: 10.1101/gad.7.7a.1111. Genes Dev. 1993. PMID: 8319904
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