Harney JW - Search Results

1

The selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism.

Luongo C, Martin C, Vella K, Marsili A, Ambrosio R, Dentice M, Harney JW, Salvatore D, Zavacki AM, Larsen PR. Luongo C, et al. Among authors: harney jw. Endocrinology. 2015 Feb;156(2):745-54. doi: 10.1210/en.2014-1698. Epub 2014 Dec 2. Endocrinology. 2015. PMID: 25456070 Free PMC article.

2

Disrupted brain thyroid hormone homeostasis and altered thyroid hormone-dependent brain gene expression in autism spectrum disorders.

Khan A, Harney JW, Zavacki AM, Sajdel-Sulkowska EM. Khan A, et al. Among authors: harney jw. J Physiol Pharmacol. 2014 Apr;65(2):257-72. J Physiol Pharmacol. 2014. PMID: 24781735 Free article.

3

Inflammation-inducible type 2 deiodinase expression in the leptomeninges, choroid plexus, and at brain blood vessels in male rodents.

Wittmann G, Harney JW, Singru PS, Nouriel SS, Reed Larsen P, Lechan RM. Wittmann G, et al. Among authors: harney jw. Endocrinology. 2014 May;155(5):2009-19. doi: 10.1210/en.2013-2154. Epub 2014 Mar 6. Endocrinology. 2014. PMID: 24601886 Free PMC article.

4

Catalysis leads to posttranslational inactivation of the type 1 deiodinase and alters its conformation.

Zhu B, Shrivastava A, Luongo C, Chen T, Harney JW, Marsili A, Tran TV, Bhadouria A, Mopala R, Steen AI, Larsen PR, Zavacki AM. Zhu B, et al. Among authors: harney jw. J Endocrinol. 2012 Jul;214(1):87-94. doi: 10.1530/JOE-11-0459. Epub 2012 Apr 27. J Endocrinol. 2012. PMID: 22544951 Free PMC article.

5

Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase.

Marsili A, Sanchez E, Singru P, Harney JW, Zavacki AM, Lechan RM, Larsen PR. Marsili A, et al. Among authors: harney jw. J Endocrinol. 2011 Oct;211(1):73-8. doi: 10.1530/JOE-11-0248. Epub 2011 Jul 25. J Endocrinol. 2011. PMID: 21788297 Free PMC article.

6

Type II iodothyronine deiodinase provides intracellular 3,5,3'-triiodothyronine to normal and regenerating mouse skeletal muscle.

Marsili A, Tang D, Harney JW, Singh P, Zavacki AM, Dentice M, Salvatore D, Larsen PR. Marsili A, et al. Among authors: harney jw. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E818-24. doi: 10.1152/ajpendo.00292.2011. Epub 2011 Jul 19. Am J Physiol Endocrinol Metab. 2011. PMID: 21771965 Free PMC article.

7

Mice with a targeted deletion of the type 2 deiodinase are insulin resistant and susceptible to diet induced obesity.

Marsili A, Aguayo-Mazzucato C, Chen T, Kumar A, Chung M, Lunsford EP, Harney JW, Van-Tran T, Gianetti E, Ramadan W, Chou C, Bonner-Weir S, Larsen PR, Silva JE, Zavacki AM. Marsili A, et al. Among authors: harney jw. PLoS One. 2011;6(6):e20832. doi: 10.1371/journal.pone.0020832. Epub 2011 Jun 16. PLoS One. 2011. PMID: 21698184 Free PMC article.

8

Physiological role and regulation of iodothyronine deiodinases: a 2011 update.

Marsili A, Zavacki AM, Harney JW, Larsen PR. Marsili A, et al. Among authors: harney jw. J Endocrinol Invest. 2011 May;34(5):395-407. doi: 10.1007/BF03347465. Epub 2011 Mar 21. J Endocrinol Invest. 2011. PMID: 21427525 Free PMC article. Review.

9

Type 2 iodothyronine deiodinase levels are higher in slow-twitch than fast-twitch mouse skeletal muscle and are increased in hypothyroidism.

Marsili A, Ramadan W, Harney JW, Mulcahey M, Castroneves LA, Goemann IM, Wajner SM, Huang SA, Zavacki AM, Maia AL, Dentice M, Salvatore D, Silva JE, Larsen PR. Marsili A, et al. Among authors: harney jw. Endocrinology. 2010 Dec;151(12):5952-60. doi: 10.1210/en.2010-0631. Epub 2010 Sep 29. Endocrinology. 2010. PMID: 20881246 Free PMC article.

10

Substitution of serine for proline in the active center of type 2 iodothyronine deiodinase substantially alters its in vitro biochemical properties with dithiothreitol but not its function in intact cells.

Goemann IM, Gereben B, Harney JW, Zhu B, Maia AL, Larsen PR. Goemann IM, et al. Among authors: harney jw. Endocrinology. 2010 Feb;151(2):821-9. doi: 10.1210/en.2009-0980. Epub 2009 Dec 4. Endocrinology. 2010. PMID: 19966180 Free PMC article.

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