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VEGF-A splicing: the key to anti-angiogenic therapeutics?
Harper SJ, Bates DO. Harper SJ, et al. Nat Rev Cancer. 2008 Nov;8(11):880-7. doi: 10.1038/nrc2505. Epub 2008 Oct 16. Nat Rev Cancer. 2008. PMID: 18923433 Free PMC article. Review.
Heterogeneous vascular endothelial growth factor (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant.
Whittle C, Gillespie K, Harrison R, Mathieson PW, Harper SJ. Whittle C, et al. Among authors: harper sj. Clin Sci (Lond). 1999 Sep;97(3):303-12. Clin Sci (Lond). 1999. PMID: 10464055
Expression of neuropilin-1 by human glomerular epithelial cells in vitro and in vivo.
Harper SJ, Xing CY, Whittle C, Parry R, Gillatt D, Peat D, Mathieson PW. Harper SJ, et al. Clin Sci (Lond). 2001 Oct;101(4):439-46. Clin Sci (Lond). 2001. PMID: 11566082
Elevated plasma vascular endothelial growth factor levels in non-diabetic predialysis uraemia.
Harper SJ, Downs L, Tomson CR, Dwight JS, Bolton C. Harper SJ, et al. Nephron. 2002 Mar;90(3):341-3. doi: 10.1159/000049071. Nephron. 2002. PMID: 11867956
VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma.
Bates DO, Cui TG, Doughty JM, Winkler M, Sugiono M, Shields JD, Peat D, Gillatt D, Harper SJ. Bates DO, et al. Among authors: harper sj. Cancer Res. 2002 Jul 15;62(14):4123-31. Cancer Res. 2002. PMID: 12124351
ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity.
Whittles CE, Pocock TM, Wedge SR, Kendrew J, Hennequin LF, Harper SJ, Bates DO. Whittles CE, et al. Among authors: harper sj. Microcirculation. 2002 Dec;9(6):513-22. doi: 10.1038/sj.mn.7800164. Microcirculation. 2002. PMID: 12483548
Functional evidence that vascular endothelial growth factor may act as an autocrine factor on human podocytes.
Foster RR, Hole R, Anderson K, Satchell SC, Coward RJ, Mathieson PW, Gillatt DA, Saleem MA, Bates DO, Harper SJ. Foster RR, et al. Among authors: harper sj. Am J Physiol Renal Physiol. 2003 Jun;284(6):F1263-73. doi: 10.1152/ajprenal.00276.2002. Epub 2003 Mar 4. Am J Physiol Renal Physiol. 2003. PMID: 12620928
Regulation of vascular permeability by vascular endothelial growth factors.
Bates DO, Harper SJ. Bates DO, et al. Among authors: harper sj. Vascul Pharmacol. 2002 Nov;39(4-5):225-37. doi: 10.1016/s1537-1891(03)00011-9. Vascul Pharmacol. 2002. PMID: 12747962 Review.
Differentiated human podocytes endogenously express an inhibitory isoform of vascular endothelial growth factor (VEGF165b) mRNA and protein.
Cui TG, Foster RR, Saleem M, Mathieson PW, Gillatt DA, Bates DO, Harper SJ. Cui TG, et al. Among authors: harper sj. Am J Physiol Renal Physiol. 2004 Apr;286(4):F767-73. doi: 10.1152/ajprenal.00337.2003. Epub 2003 Nov 25. Am J Physiol Renal Physiol. 2004. PMID: 14644752
We recently described mRNA expression of an inhibitory splice variant of VEGF (VEGF165b) in normal kidney (Bates DO, Cui TG, Doughty JM, Winkler M, Sugiono M, Shields JD, Peat D, Gillatt D, and Harper SJ. Cancer Res 62: 4123-4131, 2002). Available anti-VEGF antibodi …
We recently described mRNA expression of an inhibitory splice variant of VEGF (VEGF165b) in normal kidney (Bates DO, Cui TG, Doughty JM, Win …
Lymphatic density and metastatic spread in human malignant melanoma.
Shields JD, Borsetti M, Rigby H, Harper SJ, Mortimer PS, Levick JR, Orlando A, Bates DO. Shields JD, et al. Among authors: harper sj. Br J Cancer. 2004 Feb 9;90(3):693-700. doi: 10.1038/sj.bjc.6601571. Br J Cancer. 2004. PMID: 14760386 Free PMC article.
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