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PKM2: a gatekeeper between growth and survival.
Harris I, McCracken S, Mak TW. Harris I, et al. Cell Res. 2012 Mar;22(3):447-9. doi: 10.1038/cr.2011.203. Epub 2011 Dec 20. Cell Res. 2012. PMID: 22184007 Free PMC article. No abstract available.
Regulation of cancer cell metabolism.
Cairns RA, Harris IS, Mak TW. Cairns RA, et al. Among authors: harris is. Nat Rev Cancer. 2011 Feb;11(2):85-95. doi: 10.1038/nrc2981. Nat Rev Cancer. 2011. PMID: 21258394 Review.
Cancer cell metabolism.
Cairns RA, Harris I, McCracken S, Mak TW. Cairns RA, et al. Cold Spring Harb Symp Quant Biol. 2011;76:299-311. doi: 10.1101/sqb.2011.76.012856. Epub 2011 Dec 12. Cold Spring Harb Symp Quant Biol. 2011. PMID: 22156302 Review.
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.
Harris IS, Treloar AE, Inoue S, Sasaki M, Gorrini C, Lee KC, Yung KY, Brenner D, Knobbe-Thomsen CB, Cox MA, Elia A, Berger T, Cescon DW, Adeoye A, Brüstle A, Molyneux SD, Mason JM, Li WY, Yamamoto K, Wakeham A, Berman HK, Khokha R, Done SJ, Kavanagh TJ, Lam CW, Mak TW. Harris IS, et al. Cancer Cell. 2015 Feb 9;27(2):211-22. doi: 10.1016/j.ccell.2014.11.019. Epub 2015 Jan 22. Cancer Cell. 2015. PMID: 25620030 Free article.
Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.
Itsumi M, Inoue S, Elia AJ, Murakami K, Sasaki M, Lind EF, Brenner D, Harris IS, Chio II, Afzal S, Cairns RA, Cescon DW, Elford AR, Ye J, Lang PA, Li WY, Wakeham A, Duncan GS, Haight J, You-Ten A, Snow B, Yamamoto K, Ohashi PS, Mak TW. Itsumi M, et al. Among authors: harris is. Cell Death Differ. 2015 Nov;22(11):1837-45. doi: 10.1038/cdd.2015.38. Epub 2015 Apr 17. Cell Death Differ. 2015. PMID: 25882048 Free PMC article.
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics.
Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, Reifenberger G, Ohashi PS, Barber DL, Figueroa ME, Melnick A, Zúñiga-Pflücker JC, Mak TW. Sasaki M, et al. Among authors: harris is. Nature. 2012 Aug 30;488(7413):656-9. doi: 10.1038/nature11323. Nature. 2012. PMID: 22763442 Free PMC article.
78 results