The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling.
Macdonald A, Crowder K, Street A, McCormick C, Saksela K, Harris M.
Macdonald A, et al. Among authors: harris m.
J Biol Chem. 2003 May 16;278(20):17775-84. doi: 10.1074/jbc.M210900200. Epub 2003 Mar 5.
J Biol Chem. 2003.
PMID: 12621033
Free article.
Of particular interest is the observation that a highly conserved C-terminal Class II polyproline motif within NS5A mediated association with the Src homology 3 domains of members of the Src family of tyrosine kinases and the mitogenic adaptor protein Grb2 (A. Macdonald, K. Crowd …
Of particular interest is the observation that a highly conserved C-terminal Class II polyproline motif within NS5A mediated association wit …