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Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands.
Harrison CA, Al-Musawi SL, Walton KL. Harrison CA, et al. Growth Factors. 2011 Oct;29(5):174-86. doi: 10.3109/08977194.2011.608666. Epub 2011 Aug 24. Growth Factors. 2011. PMID: 21864080
Modulation of activin and BMP signaling.
Harrison CA, Wiater E, Gray PC, Greenwald J, Choe S, Vale W. Harrison CA, et al. Mol Cell Endocrinol. 2004 Oct 15;225(1-2):19-24. doi: 10.1016/j.mce.2004.02.008. Mol Cell Endocrinol. 2004. PMID: 15451563 Review.
Antagonists of activin signaling: mechanisms and potential biological applications.
Harrison CA, Gray PC, Vale WW, Robertson DM. Harrison CA, et al. Trends Endocrinol Metab. 2005 Mar;16(2):73-8. doi: 10.1016/j.tem.2005.01.003. Trends Endocrinol Metab. 2005. PMID: 15734148 Review.
Activins and inhibins and their signaling.
Vale W, Wiater E, Gray P, Harrison C, Bilezikjian L, Choe S. Vale W, et al. Among authors: harrison c. Ann N Y Acad Sci. 2004 Dec;1038:142-7. doi: 10.1196/annals.1315.023. Ann N Y Acad Sci. 2004. PMID: 15838109
An activin-A/C chimera exhibits activin and myostatin antagonistic properties.
Muenster U, Harrison CA, Donaldson C, Vale W, Fischer WH. Muenster U, et al. Among authors: harrison ca. J Biol Chem. 2005 Nov 4;280(44):36626-32. doi: 10.1074/jbc.M507236200. Epub 2005 Aug 29. J Biol Chem. 2005. PMID: 16129674
Rodent adrenocortical cells display high affinity binding sites and proteins for inhibin A, and express components required for autocrine signalling by activins and bone morphogenetic proteins.
Farnworth PG, Wang Y, Leembruggen P, Ooi GT, Harrison C, Robertson DM, Findlay JK. Farnworth PG, et al. Among authors: harrison c. J Endocrinol. 2006 Mar;188(3):451-65. doi: 10.1677/joe.1.06444. J Endocrinol. 2006. PMID: 16522726
Activin-A binds follistatin and type II receptors through overlapping binding sites: generation of mutants with isolated binding activities.
Harrison CA, Chan KL, Robertson DM. Harrison CA, et al. Endocrinology. 2006 Jun;147(6):2744-53. doi: 10.1210/en.2006-0131. Epub 2006 Mar 9. Endocrinology. 2006. PMID: 16527838
Identification of distinct inhibin and transforming growth factor beta-binding sites on betaglycan: functional separation of betaglycan co-receptor actions.
Wiater E, Harrison CA, Lewis KA, Gray PC, Vale WW. Wiater E, et al. Among authors: harrison ca. J Biol Chem. 2006 Jun 23;281(25):17011-22. doi: 10.1074/jbc.M601459200. Epub 2006 Apr 18. J Biol Chem. 2006. PMID: 16621788
Inhibin A and B in vitro bioactivities are modified by their degree of glycosylation and their affinities to betaglycan.
Makanji Y, Harrison CA, Stanton PG, Krishna R, Robertson DM. Makanji Y, et al. Among authors: harrison ca. Endocrinology. 2007 May;148(5):2309-16. doi: 10.1210/en.2006-1612. Epub 2007 Feb 1. Endocrinology. 2007. PMID: 17272393
Suppression of inhibin A biological activity by alterations in the binding site for betaglycan.
Makanji Y, Walton KL, Wilce MC, Chan KL, Robertson DM, Harrison CA. Makanji Y, et al. Among authors: harrison ca. J Biol Chem. 2008 Jun 13;283(24):16743-51. doi: 10.1074/jbc.M801045200. Epub 2008 Apr 7. J Biol Chem. 2008. PMID: 18397882
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