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Legionella spp. outdoors: colonization, communication and persistence.
Hilbi H, Hoffmann C, Harrison CF. Hilbi H, et al. Environ Microbiol Rep. 2011 Jun;3(3):286-96. doi: 10.1111/j.1758-2229.2011.00247.x. Epub 2011 Mar 21. Environ Microbiol Rep. 2011. PMID: 23761274
The Legionella pneumophila orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit.
Kessler A, Schell U, Sahr T, Tiaden A, Harrison C, Buchrieser C, Hilbi H. Kessler A, et al. Environ Microbiol. 2013 Feb;15(2):646-62. doi: 10.1111/j.1462-2920.2012.02889.x. Epub 2012 Oct 4. Environ Microbiol. 2013. PMID: 23033905
Exploring anti-bacterial compounds against intracellular Legionella.
Harrison CF, Kicka S, Trofimov V, Berschl K, Ouertatani-Sakouhi H, Ackermann N, Hedberg C, Cosson P, Soldati T, Hilbi H. Harrison CF, et al. PLoS One. 2013 Sep 13;8(9):e74813. doi: 10.1371/journal.pone.0074813. eCollection 2013. PLoS One. 2013. PMID: 24058631 Free PMC article.
Activation of Ran GTPase by a Legionella effector promotes microtubule polymerization, pathogen vacuole motility and infection.
Rothmeier E, Pfaffinger G, Hoffmann C, Harrison CF, Grabmayr H, Repnik U, Hannemann M, Wölke S, Bausch A, Griffiths G, Müller-Taubenberger A, Itzen A, Hilbi H. Rothmeier E, et al. Among authors: harrison cf. PLoS Pathog. 2013 Sep;9(9):e1003598. doi: 10.1371/journal.ppat.1003598. Epub 2013 Sep 19. PLoS Pathog. 2013. PMID: 24068924 Free PMC article.
The natural alternative: protozoa as cellular models for Legionella infection.
Hoffmann C, Harrison CF, Hilbi H. Hoffmann C, et al. Among authors: harrison cf. Cell Microbiol. 2014 Jan;16(1):15-26. doi: 10.1111/cmi.12235. Cell Microbiol. 2014. PMID: 24168696 Review.
Beyond Rab GTPases Legionella activates the small GTPase Ran to promote microtubule polymerization, pathogen vacuole motility, and infection.
Hilbi H, Rothmeier E, Hoffmann C, Harrison CF. Hilbi H, et al. Among authors: harrison cf. Small GTPases. 2014;5(3):1-6. doi: 10.4161/21541248.2014.972859. Small GTPases. 2014. PMID: 25496424 Free PMC article.
Adrenergic antagonists restrict replication of Legionella.
Harrison CF, Kicka S, Kranjc A, Finsel I, Chiriano G, Ouertatani-Sakouhi H, Soldati T, Scapozza L, Hilbi H. Harrison CF, et al. Microbiology. 2015 Jul;161(7):1392-406. doi: 10.1099/mic.0.000094. Epub 2015 Apr 14. Microbiology. 2015. PMID: 25873585
Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila.
Harrison CF, Chiriano G, Finsel I, Manske C, Hoffmann C, Steiner B, Kranjc A, Patthey-Vuadens O, Kicka S, Trofimov V, Ouertatani-Sakouhi H, Soldati T, Scapozza L, Hilbi H. Harrison CF, et al. ACS Infect Dis. 2015 Jul 10;1(7):327-38. doi: 10.1021/acsinfecdis.5b00002. Epub 2015 May 16. ACS Infect Dis. 2015. PMID: 27622823
Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection.
Swart AL, Harrison CF, Eichinger L, Steinert M, Hilbi H. Swart AL, et al. Among authors: harrison cf. Front Cell Infect Microbiol. 2018 Mar 2;8:61. doi: 10.3389/fcimb.2018.00061. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 29552544 Free PMC article. Review.
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