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In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.
Franks JL, Martinez-Chacin RC, Wang X, Tiedemann RL, Bonacci T, Choudhury R, Bolhuis DL, Enrico TP, Mouery RD, Damrauer JS, Yan F, Harrison JS, Major MB, Hoadley KA, Suzuki A, Rothbart SB, Brown NG, Emanuele MJ. Franks JL, et al. Among authors: harrison js. PLoS Biol. 2020 Dec 11;18(12):e3000975. doi: 10.1371/journal.pbio.3000975. eCollection 2020 Dec. PLoS Biol. 2020. PMID: 33306668 Free PMC article.
Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Brown NG, VanderLinden R, Watson ER, Weissmann F, Ordureau A, Wu KP, Zhang W, Yu S, Mercredi PY, Harrison JS, Davidson IF, Qiao R, Lu Y, Dube P, Brunner MR, Grace CRR, Miller DJ, Haselbach D, Jarvis MA, Yamaguchi M, Yanishevski D, Petzold G, Sidhu SS, Kuhlman B, Kirschner MW, Harper JW, Peters JM, Stark H, Schulman BA. Brown NG, et al. Among authors: harrison js. Cell. 2016 Jun 2;165(6):1440-1453. doi: 10.1016/j.cell.2016.05.037. Cell. 2016. PMID: 27259151 Free PMC article.
p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2.
Cloer EW, Siesser PF, Cousins EM, Goldfarb D, Mowrey DD, Harrison JS, Weir SJ, Dokholyan NV, Major MB. Cloer EW, et al. Among authors: harrison js. Mol Cell Biol. 2018 Oct 29;38(22):e00644-17. doi: 10.1128/MCB.00644-17. Print 2018 Nov 15. Mol Cell Biol. 2018. PMID: 30126895 Free PMC article.
156 results