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Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior.
Homanics GE, DeLorey TM, Firestone LL, Quinlan JJ, Handforth A, Harrison NL, Krasowski MD, Rick CE, Korpi ER, Mäkelä R, Brilliant MH, Hagiwara N, Ferguson C, Snyder K, Olsen RW. Homanics GE, et al. Among authors: harrison nl. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):4143-8. doi: 10.1073/pnas.94.8.4143. Proc Natl Acad Sci U S A. 1997. PMID: 9108119 Free PMC article.
Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol.
Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, Harris RA, Homanics GE. Werner DF, et al. Among authors: harrison nl. J Pharmacol Exp Ther. 2006 Oct;319(1):219-27. doi: 10.1124/jpet.106.106161. Epub 2006 Jun 19. J Pharmacol Exp Ther. 2006. PMID: 16785315
170 results