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1,348 results
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Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor.
Hart S, Fischer OM, Ullrich A. Hart S, et al. Cancer Res. 2004 Mar 15;64(6):1943-50. doi: 10.1158/0008-5472.can-03-3720. Cancer Res. 2004. PMID: 15026328
GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways.
Hart S, Fischer OM, Prenzel N, Zwick-Wallasch E, Schneider M, Hennighausen L, Ullrich A. Hart S, et al. Biol Chem. 2005 Sep;386(9):845-55. doi: 10.1515/BC.2005.099. Biol Chem. 2005. PMID: 16164409
Dissecting the epidermal growth factor receptor signal transactivation pathway.
Fischer OM, Hart S, Ullrich A. Fischer OM, et al. Among authors: hart s. Methods Mol Biol. 2006;327:85-97. doi: 10.1385/1-59745-012-X:85. Methods Mol Biol. 2006. PMID: 16780214
EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing.
Ruhe JE, Streit S, Hart S, Ullrich A. Ruhe JE, et al. Among authors: hart s. Cell Signal. 2006 Sep;18(9):1515-27. doi: 10.1016/j.cellsig.2005.12.003. Epub 2006 Feb 14. Cell Signal. 2006. PMID: 16478662
Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor.
Fischer OM, Hart S, Gschwind A, Prenzel N, Ullrich A. Fischer OM, et al. Among authors: hart s. Mol Cell Biol. 2004 Jun;24(12):5172-83. doi: 10.1128/MCB.24.12.5172-5183.2004. Mol Cell Biol. 2004. PMID: 15169883 Free PMC article.
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. Gschwind A, et al. Among authors: hart s. EMBO J. 2003 May 15;22(10):2411-21. doi: 10.1093/emboj/cdg231. EMBO J. 2003. PMID: 12743035 Free PMC article.
Beyond Herceptin and Gleevec.
Fischer OM, Streit S, Hart S, Ullrich A. Fischer OM, et al. Among authors: hart s. Curr Opin Chem Biol. 2003 Aug;7(4):490-5. doi: 10.1016/s1367-5931(03)00082-6. Curr Opin Chem Biol. 2003. PMID: 12941424 Review.
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification.
Prenzel N, Fischer OM, Streit S, Hart S, Ullrich A. Prenzel N, et al. Among authors: hart s. Endocr Relat Cancer. 2001 Mar;8(1):11-31. doi: 10.1677/erc.0.0080011. Endocr Relat Cancer. 2001. PMID: 11350724 Review.
The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cells.
Roidl A, Foo P, Wong W, Mann C, Bechtold S, Berger HJ, Streit S, Ruhe JE, Hart S, Ullrich A, Ho HK. Roidl A, et al. Among authors: hart s. Oncogene. 2010 Mar 11;29(10):1543-52. doi: 10.1038/onc.2009.432. Epub 2009 Nov 30. Oncogene. 2010. PMID: 19946327
Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.
Zhao L, Hart S, Cheng J, Melenhorst JJ, Bierie B, Ernst M, Stewart C, Schaper F, Heinrich PC, Ullrich A, Robinson GW, Hennighausen L. Zhao L, et al. Among authors: hart s. J Biol Chem. 2004 Oct 15;279(42):44093-100. doi: 10.1074/jbc.M313131200. Epub 2004 Jul 30. J Biol Chem. 2004. PMID: 15292206
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