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Polycomb inhibits histone acetylation by CBP by binding directly to its catalytic domain.
Tie F, Banerjee R, Fu C, Stratton CA, Fang M, Harte PJ. Tie F, et al. Among authors: harte pj. Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):E744-53. doi: 10.1073/pnas.1515465113. Epub 2016 Jan 22. Proc Natl Acad Sci U S A. 2016. PMID: 26802126 Free PMC article.
Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing.
Tie F, Banerjee R, Saiakhova AR, Howard B, Monteith KE, Scacheri PC, Cosgrove MS, Harte PJ. Tie F, et al. Among authors: harte pj. Development. 2014 Mar;141(5):1129-39. doi: 10.1242/dev.102392. Development. 2014. PMID: 24550119 Free PMC article.
Polycomb silencing of the Drosophila 4E-BP gene regulates imaginal disc cell growth.
Mason-Suares H, Tie F, Yan CM, Harte PJ. Mason-Suares H, et al. Among authors: harte pj. Dev Biol. 2013 Aug 1;380(1):111-24. doi: 10.1016/j.ydbio.2013.03.011. Epub 2013 Mar 20. Dev Biol. 2013. PMID: 23523430 Free PMC article.
Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27.
Tie F, Banerjee R, Conrad PA, Scacheri PC, Harte PJ. Tie F, et al. Among authors: harte pj. Mol Cell Biol. 2012 Jun;32(12):2323-34. doi: 10.1128/MCB.06392-11. Epub 2012 Apr 9. Mol Cell Biol. 2012. PMID: 22493065 Free PMC article.
A mutation in the E(Z) methyltransferase that increases trimethylation of histone H3 lysine 27 and causes inappropriate silencing of active Polycomb target genes.
Stepanik VA, Harte PJ. Stepanik VA, et al. Among authors: harte pj. Dev Biol. 2012 Apr 15;364(2):249-58. doi: 10.1016/j.ydbio.2011.12.007. Epub 2011 Dec 11. Dev Biol. 2012. PMID: 22182520 Free article.
Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance.
Siebold AP, Banerjee R, Tie F, Kiss DL, Moskowitz J, Harte PJ. Siebold AP, et al. Among authors: harte pj. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):169-74. doi: 10.1073/pnas.0907739107. Epub 2009 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 20018689 Free PMC article.
CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.
Tie F, Banerjee R, Stratton CA, Prasad-Sinha J, Stepanik V, Zlobin A, Diaz MO, Scacheri PC, Harte PJ. Tie F, et al. Among authors: harte pj. Development. 2009 Sep;136(18):3131-41. doi: 10.1242/dev.037127. Development. 2009. PMID: 19700617 Free PMC article.
Drosophila ESC-like can substitute for ESC and becomes required for Polycomb silencing if ESC is absent.
Kurzhals RL, Tie F, Stratton CA, Harte PJ. Kurzhals RL, et al. Among authors: harte pj. Dev Biol. 2008 Jan 1;313(1):293-306. doi: 10.1016/j.ydbio.2007.10.025. Epub 2007 Oct 25. Dev Biol. 2008. PMID: 18048023 Free PMC article.
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