Hartkoorn RC - Search Results

1

Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA.

Hartkoorn RC, Pojer F, Read JA, Gingell H, Neres J, Horlacher OP, Altmann KH, Cole ST. Hartkoorn RC, et al. Nat Chem Biol. 2014 Feb;10(2):96-8. doi: 10.1038/nchembio.1405. Epub 2013 Dec 1. Nat Chem Biol. 2014. PMID: 24292073

2

Simple model for testing drugs against nonreplicating Mycobacterium tuberculosis.

Sala C, Dhar N, Hartkoorn RC, Zhang M, Ha YH, Schneider P, Cole ST. Sala C, et al. Among authors: hartkoorn rc. Antimicrob Agents Chemother. 2010 Oct;54(10):4150-8. doi: 10.1128/AAC.00821-10. Epub 2010 Aug 2. Antimicrob Agents Chemother. 2010. PMID: 20679505 Free PMC article.

3

Sigma factor F does not prevent rifampin inhibition of RNA polymerase or cause rifampin tolerance in Mycobacterium tuberculosis.

Hartkoorn RC, Sala C, Magnet SJ, Chen JM, Pojer F, Cole ST. Hartkoorn RC, et al. J Bacteriol. 2010 Oct;192(20):5472-9. doi: 10.1128/JB.00687-10. Epub 2010 Aug 20. J Bacteriol. 2010. PMID: 20729364 Free PMC article.

4

Leads for antitubercular compounds from kinase inhibitor library screens.

Magnet S, Hartkoorn RC, Székely R, Pató J, Triccas JA, Schneider P, Szántai-Kis C, Orfi L, Chambon M, Banfi D, Bueno M, Turcatti G, Kéri G, Cole ST. Magnet S, et al. Among authors: hartkoorn rc. Tuberculosis (Edinb). 2010 Nov;90(6):354-60. doi: 10.1016/j.tube.2010.09.001. Epub 2010 Oct 8. Tuberculosis (Edinb). 2010. PMID: 20934382

5

Genome-wide definition of the SigF regulon in Mycobacterium tuberculosis.

Hartkoorn RC, Sala C, Uplekar S, Busso P, Rougemont J, Cole ST. Hartkoorn RC, et al. J Bacteriol. 2012 Apr;194(8):2001-9. doi: 10.1128/JB.06692-11. Epub 2012 Feb 3. J Bacteriol. 2012. PMID: 22307756 Free PMC article.

6

Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

Blasco B, Chen JM, Hartkoorn R, Sala C, Uplekar S, Rougemont J, Pojer F, Cole ST. Blasco B, et al. PLoS Pathog. 2012;8(3):e1002621. doi: 10.1371/journal.ppat.1002621. Epub 2012 Mar 29. PLoS Pathog. 2012. PMID: 22479184 Free PMC article.

7

Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis.

Zhang M, Sala C, Hartkoorn RC, Dhar N, Mendoza-Losana A, Cole ST. Zhang M, et al. Among authors: hartkoorn rc. Antimicrob Agents Chemother. 2012 Nov;56(11):5782-9. doi: 10.1128/AAC.01125-12. Epub 2012 Aug 27. Antimicrob Agents Chemother. 2012. PMID: 22926567 Free PMC article.

8

In vitro combination studies of benzothiazinone lead compound BTZ043 against Mycobacterium tuberculosis.

Lechartier B, Hartkoorn RC, Cole ST. Lechartier B, et al. Among authors: hartkoorn rc. Antimicrob Agents Chemother. 2012 Nov;56(11):5790-3. doi: 10.1128/AAC.01476-12. Epub 2012 Aug 27. Antimicrob Agents Chemother. 2012. PMID: 22926573 Free PMC article.

9

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid.

Hartkoorn RC, Sala C, Neres J, Pojer F, Magnet S, Mukherjee R, Uplekar S, Boy-Röttger S, Altmann KH, Cole ST. Hartkoorn RC, et al. EMBO Mol Med. 2012 Oct;4(10):1032-42. doi: 10.1002/emmm.201201689. Epub 2012 Sep 17. EMBO Mol Med. 2012. PMID: 22987724 Free PMC article.

10

Towards a new combination therapy for tuberculosis with next generation benzothiazinones.

Makarov V, Lechartier B, Zhang M, Neres J, van der Sar AM, Raadsen SA, Hartkoorn RC, Ryabova OB, Vocat A, Decosterd LA, Widmer N, Buclin T, Bitter W, Andries K, Pojer F, Dyson PJ, Cole ST. Makarov V, et al. Among authors: hartkoorn rc. EMBO Mol Med. 2014 Mar;6(3):372-83. doi: 10.1002/emmm.201303575. Epub 2014 Feb 5. EMBO Mol Med. 2014. PMID: 24500695 Free PMC article.

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