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Page 1
The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay.
Beames T, Moreau M, Roberts LA, Mansouri K, Haider S, Smeltz M, Nicolas CI, Doheny D, Phillips MB, Yoon M, Becker RA, McMullen PD, Andersen ME, Clewell RA, Hartman JK. Beames T, et al. Among authors: hartman jk. Toxicol Appl Pharmacol. 2020 Jan 15;387:114774. doi: 10.1016/j.taap.2019.114774. Epub 2019 Nov 27. Toxicol Appl Pharmacol. 2020. PMID: 31783037 Free article.
Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays.
McMullen PD, Andersen ME, Cholewa B, Clewell HJ 3rd, Dunnick KM, Hartman JK, Mansouri K, Minto MS, Nicolas CI, Phillips MB, Slattery S, Yoon M, Clewell RA. McMullen PD, et al. Among authors: hartman jk. Toxicol In Vitro. 2018 Apr;48:310-317. doi: 10.1016/j.tiv.2018.01.027. Epub 2018 Jan 31. Toxicol In Vitro. 2018. PMID: 29391263 Free article. Review.
The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor.
Karlin KL, Mondal G, Hartman JK, Tyagi S, Kurley SJ, Bland CS, Hsu TY, Renwick A, Fang JE, Migliaccio I, Callaway C, Nair A, Dominguez-Vidana R, Nguyen DX, Osborne CK, Schiff R, Yu-Lee LY, Jung SY, Edwards DP, Hilsenbeck SG, Rosen JM, Zhang XH, Shaw CA, Couch FJ, Westbrook TF. Karlin KL, et al. Among authors: hartman jk. Cell Rep. 2014 Nov 20;9(4):1318-32. doi: 10.1016/j.celrep.2014.10.011. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25453754 Free PMC article.
Analgesia, pruritus, and ventilation exhibit a dose-response relationship in parturients receiving intrathecal fentanyl during labor.
Herman NL, Choi KC, Affleck PJ, Calicott R, Brackin R, Singhal A, Andreasen A, Gadalla F, Fong J, Gomillion MC, Hartman JK, Koff HD, Lee SH, Van Decar TK. Herman NL, et al. Among authors: hartman jk. Anesth Analg. 1999 Aug;89(2):378-83. doi: 10.1097/00000539-199908000-00024. Anesth Analg. 1999. PMID: 10439751 Clinical Trial.