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The Hippo pathway and human cancer.
Harvey KF, Zhang X, Thomas DM. Harvey KF, et al. Nat Rev Cancer. 2013 Apr;13(4):246-57. doi: 10.1038/nrc3458. Epub 2013 Mar 7. Nat Rev Cancer. 2013. PMID: 23467301 Review.
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines.
Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber D, Hariharan IK. Tapon N, et al. Among authors: harvey kf. Cell. 2002 Aug 23;110(4):467-78. doi: 10.1016/s0092-8674(02)00824-3. Cell. 2002. PMID: 12202036
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis.
Harvey KF, Pfleger CM, Hariharan IK. Harvey KF, et al. Cell. 2003 Aug 22;114(4):457-67. doi: 10.1016/s0092-8674(03)00557-9. Cell. 2003. PMID: 12941274
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway.
Bennett FC, Harvey KF. Bennett FC, et al. Among authors: harvey kf. Curr Biol. 2006 Nov 7;16(21):2101-10. doi: 10.1016/j.cub.2006.09.045. Epub 2006 Oct 12. Curr Biol. 2006. PMID: 17045801
The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network.
Harvey K, Tapon N. Harvey K, et al. Nat Rev Cancer. 2007 Mar;7(3):182-91. doi: 10.1038/nrc2070. Nat Rev Cancer. 2007. PMID: 17318211 Review.
FOXO-regulated transcription restricts overgrowth of Tsc mutant organs.
Harvey KF, Mattila J, Sofer A, Bennett FC, Ramsey MR, Ellisen LW, Puig O, Hariharan IK. Harvey KF, et al. J Cell Biol. 2008 Feb 25;180(4):691-6. doi: 10.1083/jcb.200710100. J Cell Biol. 2008. PMID: 18299344 Free PMC article.
Making brundlefly, one gene at a time.
Zhang X, Richardson HE, Harvey KF. Zhang X, et al. Among authors: harvey kf. Cell Res. 2009 Jan;19(1):5-7. doi: 10.1038/cr.2009.2. Cell Res. 2009. PMID: 19125154 No abstract available.
Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines.
Zhang X, Milton CC, Humbert PO, Harvey KF. Zhang X, et al. Among authors: harvey kf. Cancer Res. 2009 Aug 1;69(15):6033-41. doi: 10.1158/0008-5472.CAN-08-4592. Epub 2009 Jul 7. Cancer Res. 2009. PMID: 19584286
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling.
Classen AK, Bunker BD, Harvey KF, Vaccari T, Bilder D. Classen AK, et al. Among authors: harvey kf. Nat Genet. 2009 Oct;41(10):1150-5. doi: 10.1038/ng.445. Epub 2009 Sep 13. Nat Genet. 2009. PMID: 19749759 Free PMC article.
Differential requirement of Salvador-Warts-Hippo pathway members for organ size control in Drosophila melanogaster.
Milton CC, Zhang X, Albanese NO, Harvey KF. Milton CC, et al. Among authors: harvey kf. Development. 2010 Mar;137(5):735-43. doi: 10.1242/dev.042309. Epub 2010 Jan 28. Development. 2010. PMID: 20110315
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