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3,539 results
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Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro.
Ono K, Hasegawa K, Naiki H, Yamada M. Ono K, et al. Among authors: hasegawa k. J Neurosci Res. 2004 Mar 15;75(6):742-50. doi: 10.1002/jnr.20025. J Neurosci Res. 2004. PMID: 14994335
A seed for Alzheimer amyloid in the brain.
Hayashi H, Kimura N, Yamaguchi H, Hasegawa K, Yokoseki T, Shibata M, Yamamoto N, Michikawa M, Yoshikawa Y, Terao K, Matsuzaki K, Lemere CA, Selkoe DJ, Naiki H, Yanagisawa K. Hayashi H, et al. Among authors: hasegawa k. J Neurosci. 2004 May 19;24(20):4894-902. doi: 10.1523/JNEUROSCI.0861-04.2004. J Neurosci. 2004. PMID: 15152051 Free PMC article.
Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer's beta-amyloid fibrils in vitro.
Ono K, Hasegawa K, Yoshiike Y, Takashima A, Yamada M, Naiki H. Ono K, et al. Among authors: hasegawa k. J Neurochem. 2002 May;81(3):434-40. doi: 10.1046/j.1471-4159.2002.00904.x. J Neurochem. 2002. PMID: 12065652
Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro.
Ozawa D, Nomura R, Mangione PP, Hasegawa K, Okoshi T, Porcari R, Bellotti V, Naiki H. Ozawa D, et al. Among authors: hasegawa k. Sci Rep. 2016 Jul 6;6:29077. doi: 10.1038/srep29077. Sci Rep. 2016. PMID: 27380955 Free PMC article.
[Search for antiamyloidogenic compounds based on a nucleation-dependent polymerization model].
Naiki H, Hasegawa K, Ono K, Yamada M. Naiki H, et al. Among authors: hasegawa k. Yakugaku Zasshi. 2010 Apr;130(4):503-9. doi: 10.1248/yakushi.130.503. Yakugaku Zasshi. 2010. PMID: 20371993 Review. Japanese.
Critical role of interfaces and agitation on the nucleation of Abeta amyloid fibrils at low concentrations of Abeta monomers.
Morinaga A, Hasegawa K, Nomura R, Ookoshi T, Ozawa D, Goto Y, Yamada M, Naiki H. Morinaga A, et al. Among authors: hasegawa k. Biochim Biophys Acta. 2010 Apr;1804(4):986-95. doi: 10.1016/j.bbapap.2010.01.012. Epub 2010 Jan 25. Biochim Biophys Acta. 2010. PMID: 20100601
Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's beta-amyloid fibrils in vitro.
Ono K, Hasegawa K, Naiki H, Yamada M. Ono K, et al. Among authors: hasegawa k. Neurochem Int. 2006 Mar;48(4):275-85. doi: 10.1016/j.neuint.2005.11.001. Epub 2005 Dec 15. Neurochem Int. 2006. PMID: 16343694
Kinetic analysis of the polymerization and depolymerization of beta(2)-microglobulin-related amyloid fibrils in vitro.
Yamamoto S, Hasegawa K, Yamaguchi I, Goto Y, Gejyo F, Naiki H. Yamamoto S, et al. Among authors: hasegawa k. Biochim Biophys Acta. 2005 Nov 10;1753(1):34-43. doi: 10.1016/j.bbapap.2005.07.007. Epub 2005 Jul 26. Biochim Biophys Acta. 2005. PMID: 16084781 Review.
Molecular interactions in the formation and deposition of beta2-microglobulin-related amyloid fibrils.
Naiki H, Yamamoto S, Hasegawa K, Yamaguchi I, Goto Y, Gejyo F. Naiki H, et al. Among authors: hasegawa k. Amyloid. 2005 Mar;12(1):15-25. doi: 10.1080/13506120500032352. Amyloid. 2005. PMID: 16076607 Review.
Preformed beta-amyloid fibrils are destabilized by coenzyme Q10 in vitro.
Ono K, Hasegawa K, Naiki H, Yamada M. Ono K, et al. Among authors: hasegawa k. Biochem Biophys Res Commun. 2005 Apr 29;330(1):111-6. doi: 10.1016/j.bbrc.2005.02.132. Biochem Biophys Res Commun. 2005. PMID: 15781239
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