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Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling.
Guo L, Iida A, Bhavani GS, Gowrishankar K, Wang Z, Xue JY, Wang J, Miyake N, Matsumoto N, Hasegawa T, Iizuka Y, Matsuda M, Nakashima T, Takechi M, Iseki S, Yambe S, Nishimura G, Koseki H, Shukunami C, Girisha KM, Ikegawa S. Guo L, et al. Among authors: hasegawa t. Nat Commun. 2021 Apr 6;12(1):2046. doi: 10.1038/s41467-021-22340-8. Nat Commun. 2021. PMID: 33824347 Free PMC article.
Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells.
Watarai H, Fujii S, Yamada D, Rybouchkin A, Sakata S, Nagata Y, Iida-Kobayashi M, Sekine-Kondo E, Shimizu K, Shozaki Y, Sharif J, Matsuda M, Mochiduki S, Hasegawa T, Kitahara G, Endo TA, Toyoda T, Ohara O, Harigaya K, Koseki H, Taniguchi M. Watarai H, et al. Among authors: hasegawa t. J Clin Invest. 2010 Jul;120(7):2610-8. doi: 10.1172/JCI42027. J Clin Invest. 2010. PMID: 20516640 Free PMC article.
KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.
Kamimura D, Katsunuma K, Arima Y, Atsumi T, Jiang JJ, Bando H, Meng J, Sabharwal L, Stofkova A, Nishikawa N, Suzuki H, Ogura H, Ueda N, Tsuruoka M, Harada M, Kobayashi J, Hasegawa T, Yoshida H, Koseki H, Miura I, Wakana S, Nishida K, Kitamura H, Fukada T, Hirano T, Murakami M. Kamimura D, et al. Among authors: hasegawa t. Nat Commun. 2015 Jun 17;6:7474. doi: 10.1038/ncomms8474. Nat Commun. 2015. PMID: 26081938 Free PMC article.
Novel regulation of MHC class II function in B cells.
Matsuki Y, Ohmura-Hoshino M, Goto E, Aoki M, Mito-Yoshida M, Uematsu M, Hasegawa T, Koseki H, Ohara O, Nakayama M, Toyooka K, Matsuoka K, Hotta H, Yamamoto A, Ishido S. Matsuki Y, et al. Among authors: hasegawa t. EMBO J. 2007 Feb 7;26(3):846-54. doi: 10.1038/sj.emboj.7601556. Epub 2007 Jan 25. EMBO J. 2007. PMID: 17255932 Free PMC article.
Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis.
Yasuda T, Fukada T, Nishida K, Nakayama M, Matsuda M, Miura I, Dainichi T, Fukuda S, Kabashima K, Nakaoka S, Bin BH, Kubo M, Ohno H, Hasegawa T, Ohara O, Koseki H, Wakana S, Yoshida H. Yasuda T, et al. Among authors: hasegawa t. J Clin Invest. 2016 Jun 1;126(6):2064-76. doi: 10.1172/JCI82887. Epub 2016 Apr 25. J Clin Invest. 2016. PMID: 27111231 Free PMC article.
Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice.
Matsuda M, Ono R, Iyoda T, Endo T, Iwasaki M, Tomizawa-Murasawa M, Saito Y, Kaneko A, Shimizu K, Yamada D, Ogonuki N, Watanabe T, Nakayama M, Koseki Y, Kezuka-Shiotani F, Hasegawa T, Yabe H, Kato S, Ogura A, Shultz LD, Ohara O, Taniguchi M, Koseki H, Fujii SI, Ishikawa F. Matsuda M, et al. Among authors: hasegawa t. Life Sci Alliance. 2019 Apr 1;2(2):e201800195. doi: 10.26508/lsa.201800195. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30936185 Free PMC article.
6,301 results