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The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein.
Hashimoto C, Hudson KL, Anderson KV. Hashimoto C, et al. Cell. 1988 Jan 29;52(2):269-79. doi: 10.1016/0092-8674(88)90516-8. Cell. 1988. PMID: 2449285
A SpƤtzle-processing enzyme required for toll signaling activation in Drosophila innate immunity.
Jang IH, Chosa N, Kim SH, Nam HJ, Lemaitre B, Ochiai M, Kambris Z, Brun S, Hashimoto C, Ashida M, Brey PT, Lee WJ. Jang IH, et al. Among authors: hashimoto c. Dev Cell. 2006 Jan;10(1):45-55. doi: 10.1016/j.devcel.2005.11.013. Dev Cell. 2006. PMID: 16399077
Spatial regulation of developmental signaling by a serpin.
Hashimoto C, Kim DR, Weiss LA, Miller JW, Morisato D. Hashimoto C, et al. Dev Cell. 2003 Dec;5(6):945-50. doi: 10.1016/s1534-5807(03)00338-1. Dev Cell. 2003. PMID: 14667416
The divergent U12-type spliceosome is required for pre-mRNA splicing and is essential for development in Drosophila.
Otake LR, Scamborova P, Hashimoto C, Steitz JA. Otake LR, et al. Among authors: hashimoto c. Mol Cell. 2002 Feb;9(2):439-46. doi: 10.1016/s1097-2765(02)00441-0. Mol Cell. 2002. PMID: 11864616
A serpin that regulates immune melanization in the respiratory system of Drosophila.
Tang H, Kambris Z, Lemaitre B, Hashimoto C. Tang H, et al. Among authors: hashimoto c. Dev Cell. 2008 Oct;15(4):617-26. doi: 10.1016/j.devcel.2008.08.017. Dev Cell. 2008. PMID: 18854145 Free PMC article.
Gastrulation defective is a serine protease involved in activating the receptor toll to polarize the Drosophila embryo.
Han JH, Lee SH, Tan YQ, LeMosy EK, Hashimoto C. Han JH, et al. Among authors: hashimoto c. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9093-7. doi: 10.1073/pnas.97.16.9093. Proc Natl Acad Sci U S A. 2000. PMID: 10922064 Free PMC article.
Biochemical defects of mutant nudel alleles causing early developmental arrest or dorsalization of the Drosophila embryo.
LeMosy EK, Leclerc CL, Hashimoto C. LeMosy EK, et al. Among authors: hashimoto c. Genetics. 2000 Jan;154(1):247-57. Genetics. 2000. PMID: 10628985 Free PMC article.
The nudel protease of Drosophila is required for eggshell biogenesis in addition to embryonic patterning.
LeMosy EK, Hashimoto C. LeMosy EK, et al. Among authors: hashimoto c. Dev Biol. 2000 Jan 15;217(2):352-61. doi: 10.1006/dbio.1999.9562. Dev Biol. 2000. PMID: 10625559
Signal transduction by a protease cascade.
LeMosy EK, Hong CC, Hashimoto C. LeMosy EK, et al. Among authors: hashimoto c. Trends Cell Biol. 1999 Mar;9(3):102-7. doi: 10.1016/s0962-8924(98)01494-9. Trends Cell Biol. 1999. PMID: 10201075 Review.
The maternal nudel protein of Drosophila has two distinct roles important for embryogenesis.
Hong CC, Hashimoto C. Hong CC, et al. Among authors: hashimoto c. Genetics. 1996 Aug;143(4):1653-61. Genetics. 1996. PMID: 8844153 Free PMC article.
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