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Following a diabetogenic T cell from genesis through pathogenesis.
Katz JD, Wang B, Haskins K, Benoist C, Mathis D. Katz JD, et al. Among authors: haskins k. Cell. 1993 Sep 24;74(6):1089-100. doi: 10.1016/0092-8674(93)90730-e. Cell. 1993. PMID: 8402882
Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells.
Delong T, Baker RL, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Barbour G, Bradley B, Haskins K. Delong T, et al. Among authors: haskins k. Diabetes. 2011 Sep;60(9):2325-30. doi: 10.2337/db11-0288. Epub 2011 Jul 6. Diabetes. 2011. PMID: 21734016 Free PMC article.
Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.
Stratmann T, Martin-Orozco N, Mallet-Designe V, Poirot L, McGavern D, Losyev G, Dobbs CM, Oldstone MB, Yoshida K, Kikutani H, Mathis D, Benoist C, Haskins K, Teyton L. Stratmann T, et al. Among authors: haskins k. J Clin Invest. 2003 Sep;112(6):902-14. doi: 10.1172/JCI18337. J Clin Invest. 2003. PMID: 12975475 Free PMC article.
Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones.
Yoshida K, Martin T, Yamamoto K, Dobbs C, Münz C, Kamikawaji N, Nakano N, Rammensee HG, Sasazuki T, Haskins K, Kikutani H. Yoshida K, et al. Among authors: haskins k. Int Immunol. 2002 Dec;14(12):1439-47. doi: 10.1093/intimm/dxf106. Int Immunol. 2002. PMID: 12456592
The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens.
Viret C, Mahiddine K, Baker RL, Haskins K, Guerder S. Viret C, et al. Among authors: haskins k. J Immunol. 2015 Sep 1;195(5):1964-73. doi: 10.4049/jimmunol.1401683. Epub 2015 Jul 24. J Immunol. 2015. PMID: 26209627
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
Delong T, Baker RL, He J, Barbour G, Bradley B, Haskins K. Delong T, et al. Among authors: haskins k. Diabetes. 2012 Dec;61(12):3239-46. doi: 10.2337/db12-0112. Epub 2012 Aug 21. Diabetes. 2012. PMID: 22912420 Free PMC article.
A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.
Piganelli JD, Flores SC, Cruz C, Koepp J, Batinic-Haberle I, Crapo J, Day B, Kachadourian R, Young R, Bradley B, Haskins K. Piganelli JD, et al. Among authors: haskins k. Diabetes. 2002 Feb;51(2):347-55. doi: 10.2337/diabetes.51.2.347. Diabetes. 2002. PMID: 11812741
Triggering a second T cell receptor on diabetogenic T cells can prevent induction of diabetes.
Fossati G, Cooke A, Papafio RQ, Haskins K, Stockinger B. Fossati G, et al. Among authors: haskins k. J Exp Med. 1999 Aug 16;190(4):577-83. doi: 10.1084/jem.190.4.577. J Exp Med. 1999. PMID: 10449528 Free PMC article.
Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant.
Böhme J, Haskins K, Stecha P, van Ewijk W, LeMeur M, Gerlinger P, Benoist C, Mathis D. Böhme J, et al. Among authors: haskins k. Science. 1989 Jun 9;244(4909):1179-83. doi: 10.1126/science.2499048. Science. 1989. PMID: 2499048
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