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The molecular and enzyme kinetic basis for the diminished activity of the cytochrome P450 2D6.17 (CYP2D6.17) variant. Potential implications for CYP2D6 phenotyping studies and the clinical use of CYP2D6 substrate drugs in some African populations.
Bapiro TE, Hasler JA, Ridderstr├Âm M, Masimirembwa CM. Bapiro TE, et al. Among authors: hasler ja. Biochem Pharmacol. 2002 Nov 1;64(9):1387-98. doi: 10.1016/s0006-2952(02)01351-5. Biochem Pharmacol. 2002. PMID: 12392820
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