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The role of AP-1 and epigenetics in ALCL.
Schiefer AI, Vesely P, Hassler MR, Egger G, Kenner L. Schiefer AI, et al. Among authors: hassler mr. Front Biosci (Schol Ed). 2015 Jun 1;7:226-35. Front Biosci (Schol Ed). 2015. PMID: 25961698 Review.
Poly(ADP-ribose) polymerase inhibitors in prostate and urothelial cancer.
Brönimann S, Lemberger U, Bruchbacher A, Shariat SF, Hassler MR. Brönimann S, et al. Among authors: hassler mr. Curr Opin Urol. 2020 Jul;30(4):519-526. doi: 10.1097/MOU.0000000000000776. Curr Opin Urol. 2020. PMID: 32427631
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.
Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Turner SD, Greil R, Kenner L. Merkel O, et al. Among authors: hassler mr. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16228-33. doi: 10.1073/pnas.1009719107. Epub 2010 Aug 30. Proc Natl Acad Sci U S A. 2010. PMID: 20805506 Free PMC article.
Epigenomics of cancer - emerging new concepts.
Hassler MR, Egger G. Hassler MR, et al. Biochimie. 2012 Nov;94(11):2219-30. doi: 10.1016/j.biochi.2012.05.007. Epub 2012 May 17. Biochimie. 2012. PMID: 22609632 Free PMC article. Review.
Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma.
Hassler MR, Klisaroska A, Kollmann K, Steiner I, Bilban M, Schiefer AI, Sexl V, Egger G. Hassler MR, et al. Biochimie. 2012 Nov;94(11):2297-307. doi: 10.1016/j.biochi.2012.05.029. Epub 2012 Jun 9. Biochimie. 2012. PMID: 22687603 Free PMC article. Review.
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, Schiefer AI, Hassler MR, Heider S, Amenitsch L, Thallinger C, Staber PB, Simonitsch-Klupp I, Artaker M, Lagger S, Turner SD, Pileri S, Piccaluga PP, Valent P, Messana K, Landra I, Weichhart T, Knapp S, Shehata M, Todaro M, Sexl V, Höfler G, Piva R, Medico E, Ruggeri BA, Cheng M, Eferl R, Egger G, Penninger JM, Jaeger U, Moriggl R, Inghirami G, Kenner L. Laimer D, et al. Among authors: hassler mr. Nat Med. 2012 Nov;18(11):1699-704. doi: 10.1038/nm.2966. Epub 2012 Oct 14. Nat Med. 2012. PMID: 23064464
The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis.
Unger C, Popescu R, Giessrigl B, Laimer D, Heider S, Seelinger M, Diaz R, Wallnöfer B, Egger G, Hassler M, Knöfler M, Saleh L, Sahin E, Grusch M, Fritzer-Szekeres M, Dolznig H, Frisch R, Kenner L, Kopp B, Krupitza G. Unger C, et al. Int J Oncol. 2013 Jan;42(1):338-48. doi: 10.3892/ijo.2012.1690. Epub 2012 Nov 6. Int J Oncol. 2013. PMID: 23135783
Combating the epigenome: epigenetic drugs against non-Hodgkin's lymphoma.
Hassler MR, Schiefer AI, Egger G. Hassler MR, et al. Epigenomics. 2013 Aug;5(4):397-415. doi: 10.2217/epi.13.39. Epigenomics. 2013. PMID: 23895653 Review.
Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation.
Kiss I, Unger C, Huu CN, Atanasov AG, Kramer N, Chatruphonprasert W, Brenner S, McKinnon R, Peschel A, Vasas A, Lajter I, Kain R, Saiko P, Szekeres T, Kenner L, Hassler MR, Diaz R, Frisch R, Dirsch VM, Jäger W, de Martin R, Bochkov VN, Passreiter CM, Peter-Vörösmarty B, Mader RM, Grusch M, Dolznig H, Kopp B, Zupko I, Hohmann J, Krupitza G. Kiss I, et al. Among authors: hassler mr. Cancer Lett. 2015 Jan 28;356(2 Pt B):994-1006. doi: 10.1016/j.canlet.2014.11.019. Epub 2014 Nov 15. Cancer Lett. 2015. PMID: 25444930
STAT3 regulated ARF expression suppresses prostate cancer metastasis.
Pencik J, Schlederer M, Gruber W, Unger C, Walker SM, Chalaris A, Marié IJ, Hassler MR, Javaheri T, Aksoy O, Blayney JK, Prutsch N, Skucha A, Herac M, Krämer OH, Mazal P, Grebien F, Egger G, Poli V, Mikulits W, Eferl R, Esterbauer H, Kennedy R, Fend F, Scharpf M, Braun M, Perner S, Levy DE, Malcolm T, Turner SD, Haitel A, Susani M, Moazzami A, Rose-John S, Aberger F, Merkel O, Moriggl R, Culig Z, Dolznig H, Kenner L. Pencik J, et al. Among authors: hassler mr. Nat Commun. 2015 Jul 22;6:7736. doi: 10.1038/ncomms8736. Nat Commun. 2015. PMID: 26198641 Free PMC article.
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