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The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo.
Armstrong JF, Pritchard-Jones K, Bickmore WA, Hastie ND, Bard JB. Armstrong JF, et al. Among authors: hastie nd. Mech Dev. 1993 Jan;40(1-2):85-97. doi: 10.1016/0925-4773(93)90090-k. Mech Dev. 1993. PMID: 8382938
The human PAX6 gene is mutated in two patients with aniridia.
Jordan T, Hanson I, Zaletayev D, Hodgson S, Prosser J, Seawright A, Hastie N, van Heyningen V. Jordan T, et al. Nat Genet. 1992 Aug;1(5):328-32. doi: 10.1038/ng0892-328. Nat Genet. 1992. PMID: 1302030
Equivalent expression of paternally and maternally inherited WT1 alleles in normal fetal tissue and Wilms' tumours.
Little MH, Dunn R, Byrne JA, Seawright A, Smith PJ, Pritchard-Jones K, van Heyningen V, Hastie ND. Little MH, et al. Among authors: hastie nd. Oncogene. 1992 Apr;7(4):635-41. Oncogene. 1992. PMID: 1314367
Zinc finger point mutations within the WT1 gene in Wilms tumor patients.
Little MH, Prosser J, Condie A, Smith PJ, Van Heyningen V, Hastie ND. Little MH, et al. Among authors: hastie nd. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):4791-5. doi: 10.1073/pnas.89.11.4791. Proc Natl Acad Sci U S A. 1992. PMID: 1317572 Free PMC article.
Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript.
Bickmore WA, Oghene K, Little MH, Seawright A, van Heyningen V, Hastie ND. Bickmore WA, et al. Among authors: hastie nd. Science. 1992 Jul 10;257(5067):235-7. doi: 10.1126/science.1321494. Science. 1992. PMID: 1321494
Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys-Drash syndrome--proof that a tumour-suppressor gene plays a crucial role in normal genitourinary development.
Hastie ND. Hastie ND. Hum Mol Genet. 1992 Aug;1(5):293-5. doi: 10.1093/hmg/1.5.293. Hum Mol Genet. 1992. PMID: 1338905 Review. No abstract available.
Wilms' tumour: reconciling genetics and biology.
Van Heyningen V, Hastie ND. Van Heyningen V, et al. Among authors: hastie nd. Trends Genet. 1992 Jan;8(1):16-21. doi: 10.1016/0168-9525(92)90019-z. Trends Genet. 1992. PMID: 1369730 Review.
Mouse small eye results from mutations in a paired-like homeobox-containing gene.
Hill RE, Favor J, Hogan BL, Ton CC, Saunders GF, Hanson IM, Prosser J, Jordan T, Hastie ND, van Heyningen V. Hill RE, et al. Among authors: hastie nd. Nature. 1991 Dec 19-26;354(6354):522-5. doi: 10.1038/354522a0. Nature. 1991. PMID: 1684639
Wilms' tumour as a paradigm for the relationship of cancer to development.
Pritchard-Jones K, Hastie ND. Pritchard-Jones K, et al. Among authors: hastie nd. Cancer Surv. 1990;9(3):555-78. Cancer Surv. 1990. PMID: 1966278 Review.
CpG islands surround a DNA segment located between translocation breakpoints associated with genitourinary dysplasia and aniridia.
Bickmore WA, Porteous DJ, Christie S, Seawright A, Fletcher JM, Maule JC, Couillin P, Junien C, Hastie ND, van Heyningen V. Bickmore WA, et al. Among authors: hastie nd. Genomics. 1989 Nov;5(4):685-93. doi: 10.1016/0888-7543(89)90109-2. Genomics. 1989. PMID: 2556343
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