Hastings ML - Search Results

1

Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis.

Geraets RD, Koh Sy, Hastings ML, Kielian T, Pearce DA, Weimer JM. Geraets RD, et al. Among authors: hastings ml. Orphanet J Rare Dis. 2016 Apr 16;11:40. doi: 10.1186/s13023-016-0414-2. Orphanet J Rare Dis. 2016. PMID: 27083890 Free PMC article. Review.

2

Searching for novel biomarkers using a mouse model of CLN3-Batten disease.

Timm D, Cain JT, Geraets RD, White KA, Koh SY, Kielian T, Pearce DA, Hastings ML, Weimer JM. Timm D, et al. Among authors: hastings ml. PLoS One. 2018 Aug 7;13(8):e0201470. doi: 10.1371/journal.pone.0201470. eCollection 2018. PLoS One. 2018. PMID: 30086172 Free PMC article.

3

Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.

Centa JL, Jodelka FM, Hinrich AJ, Johnson TB, Ochaba J, Jackson M, Duelli DM, Weimer JM, Rigo F, Hastings ML. Centa JL, et al. Among authors: hastings ml. Nat Med. 2020 Sep;26(9):1444-1451. doi: 10.1038/s41591-020-0986-1. Epub 2020 Jul 27. Nat Med. 2020. PMID: 32719489 Free PMC article.

4

Targeting RNA splicing for disease therapy.

Havens MA, Duelli DM, Hastings ML. Havens MA, et al. Among authors: hastings ml. Wiley Interdiscip Rev RNA. 2013 May-Jun;4(3):247-66. doi: 10.1002/wrna.1158. Epub 2013 Mar 19. Wiley Interdiscip Rev RNA. 2013. PMID: 23512601 Free PMC article. Review.

5

Splice-switching antisense oligonucleotides as therapeutic drugs.

Havens MA, Hastings ML. Havens MA, et al. Among authors: hastings ml. Nucleic Acids Res. 2016 Aug 19;44(14):6549-63. doi: 10.1093/nar/gkw533. Epub 2016 Jun 10. Nucleic Acids Res. 2016. PMID: 27288447 Free PMC article. Review.

6

Induction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation.

Vorlová S, Rocco G, Lefave CV, Jodelka FM, Hess K, Hastings ML, Henke E, Cartegni L. Vorlová S, et al. Among authors: hastings ml. Mol Cell. 2011 Sep 16;43(6):927-39. doi: 10.1016/j.molcel.2011.08.009. Mol Cell. 2011. PMID: 21925381 Free PMC article.

7

Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse.

Depreux FF, Wang L, Jiang H, Jodelka FM, Rosencrans RF, Rigo F, Lentz JJ, Brigande JV, Hastings ML. Depreux FF, et al. Among authors: hastings ml. Nucleic Acids Res. 2016 Nov 16;44(20):9519-9529. doi: 10.1093/nar/gkw867. Epub 2016 Sep 28. Nucleic Acids Res. 2016. PMID: 27683224 Free PMC article.

8

Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c.

Pan B, Askew C, Galvin A, Heman-Ackah S, Asai Y, Indzhykulian AA, Jodelka FM, Hastings ML, Lentz JJ, Vandenberghe LH, Holt JR, Géléoc GS. Pan B, et al. Among authors: hastings ml. Nat Biotechnol. 2017 Mar;35(3):264-272. doi: 10.1038/nbt.3801. Epub 2017 Feb 6. Nat Biotechnol. 2017. PMID: 28165476 Free PMC article.

9

Rescue of peripheral vestibular function in Usher syndrome mice using a splice-switching antisense oligonucleotide.

Vijayakumar S, Depreux FF, Jodelka FM, Lentz JJ, Rigo F, Jones TA, Hastings ML. Vijayakumar S, et al. Among authors: hastings ml. Hum Mol Genet. 2017 Sep 15;26(18):3482-3494. doi: 10.1093/hmg/ddx234. Hum Mol Genet. 2017. PMID: 28633508 Free PMC article.

10

Rescue of Outer Hair Cells with Antisense Oligonucleotides in Usher Mice Is Dependent on Age of Treatment.

Ponnath A, Depreux FF, Jodelka FM, Rigo F, Farris HE, Hastings ML, Lentz JJ. Ponnath A, et al. Among authors: hastings ml. J Assoc Res Otolaryngol. 2018 Feb;19(1):1-16. doi: 10.1007/s10162-017-0640-x. Epub 2017 Oct 12. J Assoc Res Otolaryngol. 2018. PMID: 29027038 Free PMC article.

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