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Rapamycin extends life span of Rb1+/- mice by inhibiting neuroendocrine tumors.
Livi CB, Hardman RL, Christy BA, Dodds SG, Jones D, Williams C, Strong R, Bokov A, Javors MA, Ikeno Y, Hubbard G, Hasty P, Sharp ZD. Livi CB, et al. Among authors: hasty p. Aging (Albany NY). 2013 Feb;5(2):100-10. doi: 10.18632/aging.100533. Aging (Albany NY). 2013. PMID: 23454836 Free PMC article.
Rapamycin: the cure for all that ails.
Hasty P. Hasty P. J Mol Cell Biol. 2010 Feb;2(1):17-9. doi: 10.1093/jmcb/mjp033. Epub 2009 Oct 4. J Mol Cell Biol. 2010. PMID: 19805415
mTORC1 and p53: clash of the gods?
Hasty P, Sharp ZD, Curiel TJ, Campisi J. Hasty P, et al. Cell Cycle. 2013 Jan 1;12(1):20-5. doi: 10.4161/cc.22912. Cell Cycle. 2013. PMID: 23255104 Free PMC article.
p53 as an intervention target for cancer and aging.
Hasty P, Christy BA. Hasty P, et al. Pathobiol Aging Age Relat Dis. 2013 Oct 8;3. doi: 10.3402/pba.v3i0.22702. Pathobiol Aging Age Relat Dis. 2013. PMID: 24124625 Free PMC article. Review.
eRapa restores a normal life span in a FAP mouse model.
Hasty P, Livi CB, Dodds SG, Jones D, Strong R, Javors M, Fischer KE, Sloane L, Murthy K, Hubbard G, Sun L, Hurez V, Curiel TJ, Sharp ZD. Hasty P, et al. Cancer Prev Res (Phila). 2014 Jan;7(1):169-78. doi: 10.1158/1940-6207.CAPR-13-0299. Epub 2013 Nov 26. Cancer Prev Res (Phila). 2014. PMID: 24282255 Free PMC article.
107 results