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Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV GP120: a new therapeutic concept to hit the achilles heel of HIV.
Balzarini J, Van Laethem K, Hatse S, Froeyen M, Peumans W, Van Damme E, Schols D. Balzarini J, et al. Among authors: hatse s. J Biol Chem. 2005 Dec 9;280(49):41005-14. doi: 10.1074/jbc.M508801200. Epub 2005 Sep 23. J Biol Chem. 2005. PMID: 16183648
Hippeastrum hybrid and Galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-N) inhibit human immunodeficiency virus (HIV) replication and select for drug-resistant viruses that show profound deletion of N-glycosylation sites in the GP120 envelope (Balzarini, J., Van Laet …
Hippeastrum hybrid and Galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-N) inhibit human immunodeficiency virus (HIV) replicati …
Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection.
Balzarini J, Hatse S, Vermeire K, Princen K, Aquaro S, Perno CF, De Clercq E, Egberink H, Vanden Mooter G, Peumans W, Van Damme E, Schols D. Balzarini J, et al. Among authors: hatse s. Antimicrob Agents Chemother. 2004 Oct;48(10):3858-70. doi: 10.1128/AAC.48.10.3858-3870.2004. Antimicrob Agents Chemother. 2004. PMID: 15388446 Free PMC article.
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