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66 results
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Polyglutamine aggregation in Huntington and related diseases.
Polling S, Hill AF, Hatters DM. Polling S, et al. Among authors: hatters dm. Adv Exp Med Biol. 2012;769:125-40. doi: 10.1007/978-1-4614-5434-2_8. Adv Exp Med Biol. 2012. PMID: 23560308 Review.
Protein misfolding inside cells: the case of huntingtin and Huntington's disease.
Hatters DM. Hatters DM. IUBMB Life. 2008 Nov;60(11):724-8. doi: 10.1002/iub.111. IUBMB Life. 2008. PMID: 18756529 Review.
Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence.
Coleman BM, Nisbet RM, Han S, Cappai R, Hatters DM, Hill AF. Coleman BM, et al. Among authors: hatters dm. Biochem Biophys Res Commun. 2009 Mar 13;380(3):564-8. doi: 10.1016/j.bbrc.2009.01.120. Epub 2009 Jan 25. Biochem Biophys Res Commun. 2009. PMID: 19285001
Conformation sensors that distinguish monomeric proteins from oligomers in live cells.
Ramdzan YM, Nisbet RM, Miller J, Finkbeiner S, Hill AF, Hatters DM. Ramdzan YM, et al. Among authors: hatters dm. Chem Biol. 2010 Apr 23;17(4):371-9. doi: 10.1016/j.chembiol.2010.03.011. Chem Biol. 2010. PMID: 20416508 Free PMC article.
Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool.
Olshina MA, Angley LM, Ramdzan YM, Tang J, Bailey MF, Hill AF, Hatters DM. Olshina MA, et al. Among authors: hatters dm. J Biol Chem. 2010 Jul 9;285(28):21807-16. doi: 10.1074/jbc.M109.084434. Epub 2010 May 5. J Biol Chem. 2010. PMID: 20444706 Free PMC article.
Sedimentation velocity analysis of amyloid oligomers and fibrils using fluorescence detection.
Mok YF, Ryan TM, Yang S, Hatters DM, Howlett GJ, Griffin MD. Mok YF, et al. Among authors: hatters dm. Methods. 2011 May;54(1):67-75. doi: 10.1016/j.ymeth.2010.10.004. Epub 2010 Nov 3. Methods. 2011. PMID: 21055469
Diagnostics for amyloid fibril formation: where to begin?
Hatters DM, Griffin MD. Hatters DM, et al. Methods Mol Biol. 2011;752:121-36. doi: 10.1007/978-1-60327-223-0_8. Methods Mol Biol. 2011. PMID: 21713634
Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.
Peters-Libeu C, Miller J, Rutenber E, Newhouse Y, Krishnan P, Cheung K, Hatters D, Brooks E, Widjaja K, Tran T, Mitra S, Arrasate M, Mosquera LA, Taylor D, Weisgraber KH, Finkbeiner S. Peters-Libeu C, et al. J Mol Biol. 2012 Aug 24;421(4-5):587-600. doi: 10.1016/j.jmb.2012.01.034. Epub 2012 Jan 28. J Mol Biol. 2012. PMID: 22306738 Free PMC article.
AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding.
Bieri M, Mobbs JI, Koay A, Louey G, Mok YF, Hatters DM, Park JT, Park KH, Neumann D, Stapleton D, Gooley PR. Bieri M, et al. Among authors: hatters dm. Biophys J. 2012 Jan 18;102(2):305-14. doi: 10.1016/j.bpj.2011.12.012. Biophys J. 2012. PMID: 22339867 Free PMC article.
Tracking protein aggregation and mislocalization in cells with flow cytometry.
Ramdzan YM, Polling S, Chia CP, Ng IH, Ormsby AR, Croft NP, Purcell AW, Bogoyevitch MA, Ng DC, Gleeson PA, Hatters DM. Ramdzan YM, et al. Among authors: hatters dm. Nat Methods. 2012 Mar 18;9(5):467-70. doi: 10.1038/nmeth.1930. Nat Methods. 2012. PMID: 22426490
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