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ASP4058, a novel agonist for sphingosine 1-phosphate receptors 1 and 5, ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile.
Yamamoto R, Okada Y, Hirose J, Koshika T, Kawato Y, Maeda M, Saito R, Hattori K, Harada H, Nagasaka Y, Morokata T. Yamamoto R, et al. Among authors: hattori k. PLoS One. 2014 Oct 27;9(10):e110819. doi: 10.1371/journal.pone.0110819. eCollection 2014. PLoS One. 2014. PMID: 25347187 Free PMC article.
ASP1126, a Novel Sphingosine-1-Phosphate-Selective Agonist With a Favorable Safety Profile, Prolongs Allograft Survival in Rats and Nonhuman Primates in Combination With Tacrolimus With a Broad Safety Margin for Bradycardia.
Okimoto A, Yamamoto R, Hirose J, Shimatani K, Koshika T, Maeda M, Hattori K, Morokata T. Okimoto A, et al. Among authors: hattori k. Transplant Proc. 2019 Jul-Aug;51(6):2081-2098. doi: 10.1016/j.transproceed.2019.05.012. Transplant Proc. 2019. PMID: 31399186
Potent and orally bioavailable CCR4 antagonists: Synthesis and structure-activity relationship study of 2-aminoquinazolines.
Yokoyama K, Ishikawa N, Igarashi S, Kawano N, Masuda N, Hamaguchi W, Yamasaki S, Koganemaru Y, Hattori K, Miyazaki T, Ogino S, Matsumoto Y, Takeuchi M, Ohta M. Yokoyama K, et al. Among authors: hattori k. Bioorg Med Chem. 2009 Jan 1;17(1):64-73. doi: 10.1016/j.bmc.2008.11.020. Epub 2008 Nov 17. Bioorg Med Chem. 2009. PMID: 19081254
1,739 results