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Year Number of Results
2004 1
2006 1
2007 1
2009 1
2013 4
2014 5
2015 1
2016 1
2017 5
2018 9
2019 8
2020 0
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Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data
Tachmazidou I, et al. Nat Genet 2019. Among authors: Hatzikotoulas K. PMID 30664745 Free PMC article.
Ten of the likely effector genes, including TGFB1 (transforming growth factor beta 1), FGF18 (fibroblast growth factor 18), CTSK (cathepsin K), and IL11 (interleukin 11), have therapeutics approved or in clinical trials, with mechanisms of action supportive of evaluation for efficacy in osteoarthritis....
Ten of the likely effector genes, including TGFB1 (transforming growth factor beta 1), FGF18 (fibroblast growth factor 18), CTSK (cathepsin …
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