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Promoter hypermethylation of the MEG3 (DLK1/MEG3) imprinted gene in multiple myeloma.
Benetatos L, Dasoula A, Hatzimichael E, Georgiou I, Syrrou M, Bourantas KL. Benetatos L, et al. Clin Lymphoma Myeloma. 2008 Jun;8(3):171-5. doi: 10.3816/CLM.2008.n.021. Clin Lymphoma Myeloma. 2008. PMID: 18650181
How detection of epigenetic alterations of blood-borne DNA could improve melanoma diagnosis.
Hatzimichael E, Syed N, Lo Nigro C, Rao B, Crook T. Hatzimichael E, et al. Expert Rev Mol Diagn. 2014 Jul;14(6):639-42. doi: 10.1586/14737159.2014.928204. Epub 2014 Jun 13. Expert Rev Mol Diagn. 2014. PMID: 24926921
CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes.
Benetatos L, Hatzimichael E, Dasoula A, Dranitsaris G, Tsiara S, Syrrou M, Georgiou I, Bourantas KL. Benetatos L, et al. Leuk Res. 2010 Feb;34(2):148-53. doi: 10.1016/j.leukres.2009.06.019. Leuk Res. 2010. PMID: 19595458
The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis.
Benetatos L, Hatzimichael E, Londin E, Vartholomatos G, Loher P, Rigoutsos I, Briasoulis E. Benetatos L, et al. Cell Mol Life Sci. 2013 Mar;70(5):795-814. doi: 10.1007/s00018-012-1080-8. Epub 2012 Jul 24. Cell Mol Life Sci. 2013. PMID: 22825660 Review.
Delta-like homologue 1 and its role in the bone marrow niche and hematologic malignancies.
Benetatos L, Hatzimichael E. Benetatos L, et al. Clin Lymphoma Myeloma Leuk. 2014 Dec;14(6):451-5. doi: 10.1016/j.clml.2014.06.019. Epub 2014 Jun 23. Clin Lymphoma Myeloma Leuk. 2014. PMID: 25066037 Review.
DLK1-DIO3 imprinted cluster in induced pluripotency: landscape in the mist.
Benetatos L, Vartholomatos G, Hatzimichael E. Benetatos L, et al. Cell Mol Life Sci. 2014 Nov;71(22):4421-30. doi: 10.1007/s00018-014-1698-9. Epub 2014 Aug 7. Cell Mol Life Sci. 2014. PMID: 25098353 Review.
Real-world data on Len/Dex combination at second-line therapy of multiple myeloma: treatment at biochemical relapse is a significant prognostic factor for progression-free survival.
Katodritou E, Kyrtsonis MC, Delimpasi S, Kyriakou D, Symeonidis A, Spanoudakis E, Vasilopoulos G, Anagnostopoulos A, Kioumi A, Zikos P, Aktypi A, Briasoulis E, Megalakaki A, Repousis P, Adamopoulos I, Gogos D, Kotsopoulou M, Pappa V, Papadaki E, Fotiou D, Nikolaou E, Giannopoulou E, Hatzimichael E, Giannakoulas N, Douka V, Kokoviadou K, Timotheatou D, Terpos E. Katodritou E, et al. Ann Hematol. 2018 Sep;97(9):1671-1682. doi: 10.1007/s00277-018-3361-2. Epub 2018 May 13. Ann Hematol. 2018. PMID: 29756171 Free PMC article.
Polo-like kinase 2 (SNK/PLK2) is a novel epigenetically regulated gene in acute myeloid leukemia and myelodysplastic syndromes: genetic and epigenetic interactions.
Benetatos L, Dasoula A, Hatzimichael E, Syed N, Voukelatou M, Dranitsaris G, Bourantas KL, Crook T. Benetatos L, et al. Ann Hematol. 2011 Sep;90(9):1037-45. doi: 10.1007/s00277-011-1193-4. Epub 2011 Feb 22. Ann Hematol. 2011. PMID: 21340720
The prolyl-hydroxylase EGLN3 and not EGLN1 is inactivated by methylation in plasma cell neoplasia.
Hatzimichael E, Dasoula A, Shah R, Syed N, Papoudou-Bai A, Coley HM, Dranitsaris G, Bourantas KL, Stebbing J, Crook T. Hatzimichael E, et al. Eur J Haematol. 2010 Jan 1;84(1):47-51. doi: 10.1111/j.1600-0609.2009.01344.x. Epub 2009 Sep 8. Eur J Haematol. 2010. PMID: 19737309
Hypercalcemia remains an adverse prognostic factor for newly diagnosed multiple myeloma patients in the era of novel antimyeloma therapies.
Zagouri F, Kastritis E, Zomas A, Terpos E, Katodritou E, Symeonidis A, Delimpasi S, Pouli A, Vassilakopoulos TP, Michalis E, Giannouli S, Kartasis Z, Christoforidou A, Kokoviadou K, Hatzimichael E, Gika D, Megalakaki C, Papaioannou M, Kyrtsonis MC, Konstantopoulos K, Dimopoulos MA; Greek Myeloma Study Group. Zagouri F, et al. Eur J Haematol. 2017 Nov;99(5):409-414. doi: 10.1111/ejh.12923. Epub 2017 Sep 26. Eur J Haematol. 2017. PMID: 28675766
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